APPD Antibody
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Catalog numberbs-6793R
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PricePlease ask
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Size0.1ml
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Long nameAPPD Primary Polyclonal Antibody
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Also known asAPPD PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenAPPD
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SpecificityThis is a highly specific antibody against APPD.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range75-125/279
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Subcellular locationCytoplasm, Nucleus, Lysosome
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APPD/ Apoptosis-inducing protein
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Gene ID number79156
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Swiss ProtQ96S99
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Tested ApplicationsIHC-P
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Recommended dilutionsIHC-P(1:100-500)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenMay induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesAPPD; LAPF; PHAFIN1; ZFYVE15; Pleckstrin homology domain-containing family F member 1; PH domain-containing family F member 1; Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; Apoptosis-inducing protein; PH and FYVE domain-containing protein 1; Phafin-1; Zinc finger FYVE domain-containing protein 15; PLEKHF1
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPLEKHF1
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Short nameAnti-APPD
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameAPPD Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namepleckstrin homology and FYVE domain containing 1
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Synonyms gene name
- pleckstrin homology domain containing, family F (with FYVE domain) member 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-04-01
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Entrez gene record
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- Zinc fingers FYVE-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data