APP (His-tagged); human recombinant

Products_type

Recombinant Protein
Products_short_name

[APP]
Products_name_syn

[ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II; Amyloid beta A4 protein]
Other_names

[amyloid beta A4 protein isoform a; Amyloid beta A4 protein; amyloid beta A4 protein; amyloid beta precursor protein; ABPP; APPI; APP]
Products_gene_name

[APP]
Other_gene_names

[APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; preA4; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)]
Purity

>85%
Form

Liquid
Concentration

1 mg/ml
Storage_stability

Store at -20 degree C for 12 months.Centrifuge the vial prior to opening.
Tested_application

SDS-PAGE
Conjugation

histidine
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

APP His-tagged
Gene symbol

APP-DT, APP, PABPC4, NAE1
Short name

APP (His-tagged); recombinant
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

E ColiSource: Human
Label

his-tagged
Species

Human, Humans
Alternative name

amyloid beta (A4) precursor protein (histidine-tagged); H. sapiens Rec.
Alternative technique

rec
Alternative to gene target

amyloid beta (A4) precursor protein, AAA and ABETA and ABPP and AD1 and APPI and CTFgamma and CVAP and PN-II and PN2, APP and IDBG-1100 and ENSG00000142192 and 351, growth factor receptor binding, nuclei, App and IDBG-172954 and ENSMUSG00000022892 and 11820, APP and IDBG-630293 and ENSBTAG00000017753 and 280722

Identity

HGNC:620
Gene

APP
Long gene name

amyloid beta precursor protein
Synonyms gene
- AD1
Synonyms gene name
- Alzheimer disease
- amyloid beta (A4) precursor protein
Synonyms
- alpha-sAPP
Synonyms name
- peptidase nexin-II
GenBank acession
- M15533
Locus

21q21.3
Discovery year

1986-01-01
Entrez gene record

351
Pubmed identfication
- 1679289
RefSeq identity
- NM_000484
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000078438
Locus Specific Databases
- Alzheimer Disease & Frontotemporal Dementia Mutation Database

Identity

HGNC:8557
Gene

PABPC4
Long gene name

poly(A) binding protein cytoplasmic 4
Synonyms gene name
- poly(A)-binding protein, cytoplasmic 4 (inducible form)
- poly(A) binding protein, cytoplasmic 4 (inducible form)
Synonyms
- iPABP
- APP-1
Synonyms name
- activated-platelet protein 1
- Inducible poly(A)-binding protein
GenBank acession
- U33818
Locus

1p34.3
Discovery year

1999-12-17
Entrez gene record

8761
Pubmed identfication
- 10543404
RefSeq identity
- NM_001135653
Classification
- RNA binding motif containing
- Small nucleolar RNA protein coding host genes
VEGA ID

OTTHUMG00000009097

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data