Apolipoprotein A-II / APOA2, Human Recombinant

• Catalog number
  P1383-10
• Price
  Please ask
• Size
  10 µg

• Synonyms
  Apolipoprotein A-II, APOA2, Apo-AII, ApoA-II, Apolipoprotein A2
• Alternative_names
  Apolipoprotein A-II, APOA2, Apo-AII, ApoA-II, Apolipoprotein A2
• Description
  Regulates HDL metabolism
• Source
  E.coli
• Purity by SDS PAGE
  >90% as determined by SDS-PAGE.
• Endotoxin Level
  Less than 1.0 EU per ug by the LAL method.
• Molecular Weight
  This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 11.2 kDa. The protein migrates as 11 kDa and 13 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Storage Temp
  -20ºC
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Lyophilized
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in sterile deionized water to a concentration of 100 µg/ml. Do not vortex. It is recommended to store at -20°C.
• Background Information
  Apolipoprotein A-II(APO-A2) stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. It is produced by the liver and is involved in cholesteryl ester formation and cholesterol transport from tissues to the liver. Recent studies have established the interaction between APOA2 -256T>C polymorphism and dietary saturated fatty acids intake in relation to obesity on healthy individuals. Significant interaction between APOA2-saturated fatty acids intake and body mass index (BMI). The result of this study confirmed the interaction between APOA2 -256T>C polymorphism and SFAs intake with BMI in type 2 diabetic patients.
• Amino acid sequence
  AA Ala 19 - Gln 100
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Apolipoprotein   A-II   APOA2  
• Gene symbol
  APOA2, MSR1, MYH9, HLA-A, IGHV5-10-1, CIDEA, RPA1, SPINK2, CRABP2, MGST2
• Short name
  Apolipoprotein A-II / APOA2, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Apolipoprotein A-II / apolipoprotein A-II, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  apolipoprotein A-II, Apo-AII and ApoA-II and apoAII, APOA2 and IDBG-104234 and ENSG00000158874 and 336, high-density lipoprotein particle receptor binding, Extracellular, Apoa2 and IDBG-204212 and ENSMUSG00000005681 and 11807, APOA2 and IDBG-630130 and ENSBTAG00000009212 and 505394

Gene info

• Identity
  HGNC:601
• Gene
  APOA2
• Long gene name
  apolipoprotein A2
• Synonyms gene name
  • apolipoprotein A-II
• Locus
  1q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  336
• Pubmed identfication
  • 2415515
• RefSeq identity
  • NM_001643
• Classification
  • Apolipoproteins
• VEGA ID
  OTTHUMG00000034346

Gene info

• Identity
  HGNC:7376
• Gene
  MSR1
• Long gene name
  macrophage scavenger receptor 1
• Synonyms
  • SCARA1
  • CD204
  • SR-AI
  • SR-AII
  • SR-AIII
  • SR-A
• GenBank acession
  • D13263
• Locus
  8p22
• Discovery year
  1991-08-07
• Pubmed identfication
  • 2251254
• Classification
  • CD molecules
  • Scavenger receptors
  • Scavenger receptor cysteine rich domain containing
• VEGA ID
  OTTHUMG00000094809

Gene info

• Identity
  HGNC:7579
• Gene
  MYH9
• Long gene name
  myosin heavy chain 9
• Synonyms gene
  • DFNA17
• Synonyms gene name
  • myosin, heavy polypeptide 9, non-muscle
• Synonyms
  • NMMHCA
  • NMHC-II-A
  • MHA
  • FTNS
  • EPSTS
• Synonyms name
  • nonmuscle myosin heavy chain II-A
• Locus
  22q12.3
• Discovery year
  1990-03-12
• Entrez gene record
  4627
• Pubmed identfication
  • 1860190
  • 11023810
• RefSeq identity
  • NM_002473
• Classification
  • Myosin heavy chains, class II
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000030429
• Locus Specific Databases
  • Hereditary Hearing Loss Homepage
  • LRG_567

Gene info

• Identity
  HGNC:4931
• Gene
  HLA-A
• Long gene name
  major histocompatibility complex, class I, A
• GenBank acession
  • D32129
• Locus
  6p22.1
• Discovery year
  2001-06-22
• Entrez gene record
  3105
• Pubmed identfication
  • 8838351
• RefSeq identity
  • NM_002116
• Classification
  • C1-set domain containing
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000130501
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:5661
• Gene
  IGHV5-10-1
• Long gene name
  immunoglobulin heavy variable 5-10-1
• Synonyms gene
  • IGHV5-A
• Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
• Synonyms
  • IGHV5-a
• GenBank acession
  • X92227
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28386
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191143

Gene info

• Identity
  HGNC:1976
• Gene
  CIDEA
• Long gene name
  cell death inducing DFFA like effector a
• Synonyms gene name
  • cell death-inducing DFFA-like effector a
• Synonyms
  • CIDE-A
• GenBank acession
  • AF041378
• Locus
  18p11.21
• Discovery year
  1998-07-15
• Entrez gene record
  1149
• Pubmed identfication
  • 9564035
  • 18509062
• RefSeq identity
  • NM_001279
• VEGA ID
  OTTHUMG00000131691

Gene info

• Identity
  HGNC:10289
• Gene
  RPA1
• Long gene name
  replication protein A1
• Synonyms gene name
  • replication protein A1 (70kD)
  • replication protein A1, 70kDa
• Synonyms
  • REPA1
  • RPA70
  • HSSB
  • RF-A
  • RP-A
• GenBank acession
  • M63488
• Locus
  17p13.3
• Discovery year
  1993-12-14
• Entrez gene record
  6117
• Pubmed identfication
  • 8454588
• RefSeq identity
  • NM_002945
• Classification
  • Nucleotide excision repair
• VEGA ID
  OTTHUMG00000090579

Gene info

• Identity
  HGNC:11245
• Gene
  SPINK2
• Long gene name
  serine peptidase inhibitor Kazal type 2
• Synonyms gene name
  • serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
• Synonyms
  • HUSI-II
• Synonyms name
  • acrosin-trypsin inhibitor
• GenBank acession
  • BC022514
• Locus
  4q12
• Discovery year
  1993-12-01
• Entrez gene record
  6691
• Pubmed identfication
  • 8428671
• RefSeq identity
  • NM_021114
• Classification
  • Serine peptidase inhibitors, Kazal type
• VEGA ID
  OTTHUMG00000128769

Gene info

• Identity
  HGNC:2339
• Gene
  CRABP2
• Long gene name
  cellular retinoic acid binding protein 2
• Synonyms gene name
  • cellular retinoic acid-binding protein 2
• Synonyms
  • CRABP-II
• GenBank acession
  • BC001109
• Locus
  1q23.1
• Discovery year
  1992-11-25
• Entrez gene record
  1382
• Pubmed identfication
  • 1654334
• RefSeq identity
  • NM_001878
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000041300

Gene info

• Identity
  HGNC:7063
• Gene
  MGST2
• Long gene name
  microsomal glutathione S-transferase 2
• Synonyms
  • MGST-II
• GenBank acession
  • U77604
• Locus
  4q31.1
• Discovery year
  1997-10-16
• Entrez gene record
  4258
• Pubmed identfication
  • 8703034
• RefSeq identity
  • NM_002413
• Classification
  • Microsomal glutathione S-transferases
• VEGA ID
  OTTHUMG00000133382

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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