Apigenin for cell activation

Apigenin for cell activation is available 2 times from Biovision labs

2508-25 | Apigenin for cell activationsize: 25 mg | 161.75 USD

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2508-100 | Apigenin for cell activationsize: 100 mg | 397.55 USD

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  • Description
    A naturally occurring plant flavone that displays remarkable anti-inflammatory, antioxidant and anti-carcinogenic properties. It selectively inhibits casein kinase II (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC₅₀ value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the degradation of IκBα and down-regulates NF-κB levels in WEHI 231 cells. At 5 µM, it is a potent inhibitor of the synthesis of the inflammatory mediators nitric oxide and prostaglandin E2, reducing inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by 56% and 64%, respectively, in the macrophage cell line J774A.1.
  • Peptide sequence
    No
  • CAS number
     520-36-5
  • Molecular weight
    270.2
  • Category
    Biochemicals
  • Other name
    5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; Chamomile; Flavone; NSC 83244; Versulin
  • Molecular formula
    C₁₅H₁₀O₅
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (~25 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    Gel pack
  • Maximum time for storage
    24 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    Apigenin for activation
  • Technique
    activation
  • Alternative name
    Apigenin to measure cellular activation
  • Alternative technique
    immunoglobulin-e
  • Tissue
    cell
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