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Chemical available in other sizes
Please inquire size and price
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Stock availability
In Stock
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Cas number
183506-66-3
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Chemical s molecular weight
623.78
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Chemical s main applications
Apicidin is a potent (nM) cell permeable inhibitor of histone deacetylase. Also, Apicidin exhibits antiprotozoal and potential antimalarial properties. Apicidin has antiproliferative activity on HeLa cells accompanied by cell arrest at the G1 phase. Apicidin induces selective changes in the expression of p21 and gelsolin.
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Chemical s category
Aromatics, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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Other name
Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]; Cyclo(8-oxo-L-2-aminodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl- D-2-piperidinecarbonyl); Apicidin Ia; OSI 2040;
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Chemical s formula
C34H49N5O6
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Physical properties
White Solid
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Melting temperature
188-190ºC
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Boiling temperature
No Data Available
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Chemical s soluble in
DMSO (Slightly), Methanol (Slightly, Heated)
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Stability conditions
No Data Available
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Storage
Refrigerator
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