Antithrombin (Native Protein)

• Catalog number
  30 900 106
• Price
  Please ask
• Size
  100 µg lyophilized

• Protein type
  Native
• Protein subtype
  N/A
• Protein family
  Inhibitor of serine proteases, Member of Serpin Family
• Protein description
  Antithrombin is the most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
• Research area interests
  Diseases associated with SERPINC1 include Thrombophilia Due To Antithrombin Iii Deficiency and Disseminated Intravascular Coagulation. Among its related pathways are Platelet activation, signaling and aggregation and Formation of Fibrin Clot (Clotting Cascade).
• Package form
  liquid
• Tested applications
  inhibitor of proteases
• Other names
  Serpin Family C Member 1, SERPINC1
• Peptide sequence
  MYSNVIGTVTSGKRKVYLLSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANPCVK
• Available target modification
  No
• Expression system
  Human Blood
• Product Subtype
  full length
• Active form
  Yes
• Tag
  untagged
• Contents
  20 mM sodium phospahte buffer pH7.4; 250 mM NaCl without BSA and Azide, free of heparin
• Protein purity
  >95%
• Molecular weight
  65 kDa
• UniProt number
  P01008
• Gene number
  462
• Abbreviation
  SERPINC1
• Full name
  serpin family C member 1
• Other desciption
  Purified from human serum.
• Purification
  Mentioned in the data sheet
• PubMed citations
  See the data sheet
• Warnings
  For Research Use only.
• Shipping conditions
  cool packs or dry ice
• Storage condition
  Store at -70°C
• Technical datasheet
  Contact us to receive the datasheet
• Representative figure
• Other products

• Gene target
  Antithrombin   Native   Protein  
• Short name
  Antithrombin (Native Protein)
• Species
  Homo sapiens
• Alternative name
  Antithrombin (Native Protein)

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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