anti-ZAP70 Antibody [3D2A4]

  • Catalog number
    32-237
  • Price
    Please ask
  • Size
    0.1 mg
  • Gene info
    ZAP70(zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
  • Gene names
    SRK, 70 kDa zeta-chain associated proteinSRK, STD, TZK, STCD, ZAP-70
  • Antibodie s label
    unlabelled serum
  • Ab raised in
    Mouse
  • Type
    Monoclonal
  • Monoclonal
    3D2A4
  • Immunoglobulin
    IgG1
  • Antigen
    Ni-NTA purified truncated recombinant ZAP70 expressed in E. Coli strain BL21 (DE3).
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry
  • Antibody advice
    Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000IHC(F):1:500 - 1:2,000ELISA:Propose dilution 1:10,000.Determining optimal working dilutions by titration test.
  • Suspention pH azide
    Ascitic fluid containing 0.03% sodium azide.
  • Keep at
    ZAP70 monoclonal antibody can be stored at -20 grades C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    1177044
  • Ncbi nr
    P43403
  • NCBI GENE nr
    7535
  • GENE symbol
    ZAP70
  • Antigene name
    zeta-chain (TCR) associated protein kinase 70kDa
  • Source
    Homo sapiens
  • Protein nr
    P43403
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    ZAP70   [3D2A4]  
  • Gene symbol
    ZAP70
  • Short name
    anti-ZAP70 Antibody [3D2A4]
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toZAP70 (antibody to-) [3D2A4]
  • Alternative technique
    antibodies
  • Alternative to gene target
    zeta-chain (TCR) associated protein kinase 70kDa, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, transferase activity, Cell surfaces, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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