anti-Zap 70 (Ab 493) Antibody

  • Catalog number
    79-348
  • Price
    Please ask
  • Size
    0.1 mg
  • Gene info
    ZAP70 is a 70-kD tyrosine phosphoprotein that associates with the ζ chain and undergoes tyrosine phosphorylation following TCR stimulation. The ZAP70 gene is expressed in T- and natural KILLER cells. Protein-Tyrosine Kinases (PTKs) play an integral role in T-cell activation. Stimulation of the T-cell antigen receptor results in tyrosine phosphorylation of a number of cellular substrates. One of these is the TCR-ζ chain, which can mediate the transduction of extracellular stimuli into cellular effector functions
  • Gene names
    SRK, STD, TZK, STCD, ZAP-70, ERBB, ERBB1, HER1, 70 kDa zeta-associated protein, SRK, Syk-related tyrosine kinase, ZA70
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Spicific to
    This antibody detects endogenous level of total Zap-70 protein.
  • Antigen
    Zap-70 (Ab-493) antibody was made against a peptide sequence around aa.491~495 (S-Y-Y-T-A) derived from Human ZAP70.
  • Immuno application
    Western Blot, immuno-histo-chemistry
  • Antibody advice
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
  • Suspention pH azide
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Keep at
    Store antibody at -20 grades C for up to one year.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    31455611
  • Ncbi nr
    NP_001070.2
  • KDa
    70 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    7535
  • GENE symbol
    ZAP70
  • Antigene name
    zeta-chain (TCR) associated protein kinase 70kDa
  • Source
    Homo sapiens
  • Protein nr
    P43403
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Zap   493  
  • Short name
    anti-Zap 70 (Ab 493) Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toZap 70 (Antibody 493) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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