Wnt-1 Antibody

  • Catalog number
    5754-100
  • Price
    Please ask
  • Size
    100 µg
  • Antibody Target
    Wnt-1
  • Target Alternative Name
    wnt1, wnt 1, wnt-1, INT 1 , INT1, wingless type MMTV integration site family member 1
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human
  • Immunogen Sequence
    E. coli expressed human Wnt-1
  • Accession
    P04628
  • Gene Id
    7471
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.5 mg/ml
  • Formulation
    100 µg (0.5 mg/ml) affinity purified rabbit anti-human Wnt-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
  • Purification
    Affinity purified
  • Application
    Western blot
  • Application And Usages
    Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Recombinant human Wnt-1 (Cat.# 4754-10) can be used as a positive control.
  • Description
    Wnt-1 is a secreted protein that signals throμgh the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt-1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenine. Wnt signaling induces and maintains the transformed phenotype and, in certain embryonic cell lines, supports self renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. Mature human Wnt-1 is a glycosylated protein containing 343 amino acid residues.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Wnt-1  
  • Gene symbol
    WIF1, NKD1, FRAT1
  • Short name
    Wnt-1 Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    Wnt-1 (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    NKD inhibitor of WNT signaling pathway 1
  • Synonyms gene name
    • naked cuticle homolog 1 (Drosophila)
    • naked cuticle homolog 1
    • NKD1, WNT signaling pathway inhibitor
  • GenBank acession
  • Locus
  • Discovery year
    2001-10-19
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • EF-hand domain containing
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    FRAT regulator of WNT signaling pathway 1
  • Synonyms gene name
    • frequently rearranged in advanced T-cell lymphomas
    • frequently rearranged in advanced T-cell lymphomas 1
    • FRAT1, WNT signaling pathway regulator
  • GenBank acession
  • Locus
  • Discovery year
    2000-04-13
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee