USP34 Core Antibody

• Catalog number
  6136-50
• Price
  Please ask
• Size
  50 μg

• Antibody Target
  USP34 Core
• Target Alternative Name
  FLJ43910, KIAA0570, KIAA0729, Ubiquitin Specific Protease 34 core domain.
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant full length protein
• Accession
  Q70CQ2
• Gene Id
  9736
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  50 µg of antibody in PBS containing 10% glycerol
• Purification
  Purified from egg yolk
• Application
  Western blot
• Application And Usages
  Western blot: Robust detection of 100 ng of recombinant protein was possible when antibody was used at a final concentration of 5 μg/mL
• Description
  USP34 Core is a ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. It acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. It recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. Its catalytic core consists of residues 1892-2241.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  USP34   Core  
• Gene symbol
  USP34-DT, USP34
• Short name
  USP34 Core Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Chicken IgG
• Alternative name
  USP34 Core (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55262
• Gene
  USP34-DT
• Long gene name
  USP34 divergent transcript
• Locus
  2p15
• Discovery year
  2020-09-27
• Entrez gene record
  105377633
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:20066
• Gene
  USP34
• Long gene name
  ubiquitin specific peptidase 34
• Synonyms gene name
  • ubiquitin specific protease 34
• Synonyms
  • KIAA0570
  • KIAA0729
• GenBank acession
  • AB011142
• Locus
  2p15
• Discovery year
  2003-09-04
• Entrez gene record
  9736
• Pubmed identfication
  • 12838346
• Classification
  • Ubiquitin specific peptidases
  • Armadillo like helical domain containing
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000152265

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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