USP2 Antibody

• Catalog number
  6141-100
• Price
  Please ask
• Size
  100 μg

• Antibody Target
  USP2
• Target Alternative Name
  USP2, UBP41, USP9
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Fusion protein of human USP2
• Accession
  O75604
• Gene Id
  9099
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µg of antibody in 100 µl PBS containing 0.02% sodium azide, 50% glycerol, pH 7.3
• Purification
  Affinity purified
• Application
  Western blot, Immunohistochemistry, Immunofluorescence
• Positive Control
  Western Blot: Liver cell lysate
• Application And Usages
  Western blot: 1:200 – 1:500 dilution, IHC: 1:50 - 1:100 dilution. IF: 1:20 - 1:50 dilution. However, the optimal conditions should be determined individually.
• Description
  Ubiquitinating enzymes (UBEs) catalyze protein ubiquitination, a reversible process countered by deubiquitinating enzymes (DUB) action. There are five DUB subfamilies including the USP, UCH, OTU, MJD, and JAMM enzymes. Ubiquitin­specific­processing protease 2 (USP2) belongs to the USP (UBP/UCH type 2) subfamily and is characterized by its C19 peptidase activity, which is involved in ubiquitin recycling and in the disassembly of various forms of polymeric ubiquitin and ubiquitin like protein complexes. There is mounting evidence that USP2 functions as an oncoprotein through multiple mechanisms. In human prostate cancer, USP2 is highly overexpressed and drives tumor growth by binding to and stabilizing fatty acid synthase through deubiquitination. It has also been demonstrated that USP2 can bind and deubiquitinate both Mdm2 and cyclin D1, which leads to their stabilization and enhanced cell proliferation.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  USP2  
• Gene symbol
  USP2, USP2-AS1
• Short name
  USP2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  USP2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12618
• Gene
  USP2
• Long gene name
  ubiquitin specific peptidase 2
• Synonyms gene name
  • ubiquitin specific protease 2
• Synonyms
  • UBP41
• GenBank acession
  • AF079564
• Locus
  11q23.3
• Discovery year
  1999-07-09
• Entrez gene record
  9099
• Pubmed identfication
  • 12838346
• RefSeq identity
  • NM_171997
• Classification
  • Ubiquitin specific peptidases
• VEGA ID
  OTTHUMG00000166200

Gene info

• Identity
  HGNC:48673
• Gene
  USP2-AS1
• Long gene name
  USP2 antisense RNA 1 (head to head)
• Synonyms
  • THY1-AS1
• Locus
  11q23.3
• Discovery year
  2013-06-06
• Entrez gene record
  100499227
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000166173

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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