UCP1 Antibody

• Catalog number
  6637-50
• Price
  Please ask
• Size
  50 μg

• Antibody Target
  UCP1
• Target Alternative Name
  Uncoupling protein 1, mitochondrial brown fat uncoupling protein 1, solute carrier family 25 member 7, SLC25A7, Thermogenin
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  UCP1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human UCP1
• Accession
  P25874
• Gene Id
  7350
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  1 mg/ml in PBS containing 0.02% sodium azide
• Purification
  Affinity chromatography purified via peptide column
• Application
  Western blot, Immunohistochemistry, ELISA
• Positive Control
  Western blot: HeLa cell lysate. Immunohistochemistry: Human liver tissue.
• Application And Usages
  Western blot: 1 - 2 µg/mL, IHC: 2.5 µg/mL, ELISA
• Description
  The mitochondrial brown fat uncoupling protein 1 (UCP1) is a member of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. UCP1 is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  UCP1  
• Gene symbol
  UCP1
• Short name
  UCP1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  uncoupling protein 1 (mitochondrial, proton carrier) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  uncoupling protein 1 (mitochondrial, proton carrier), SLC25A7 and UCP, UCP1 and IDBG-38859 and ENSG00000109424 and 7350, oxidative phosphorylation uncoupler activity, Plasma membranes, Ucp1 and IDBG-171838 and ENSMUSG00000031710 and 22227, UCP1 and IDBG-629680 and ENSBTAG00000004647 and 101910176,281561

Gene info

• Identity
  HGNC:12517
• Gene
  UCP1
• Long gene name
  uncoupling protein 1
• Synonyms gene
  • UCP
• Synonyms gene name
  • uncoupling protein 1 (mitochondrial, proton carrier)
• Synonyms
  • SLC25A7
• GenBank acession
  • X51955
• Locus
  4q31.1
• Discovery year
  1991-08-19
• Entrez gene record
  7350
• Pubmed identfication
  • 2380264
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000133415

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products