Anti-E1 Ubiquitin Activating Enzyme, ALEXA Fluor 594

• Catalog number
  GENTObs-6835R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  E1 Ubiquitin Activating Enzyme
• Specificity
  This antibody reacts specifically with E1 Ubiquitin Activating Enzyme
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic peptide derived from human UBE1
• Gene ID
  7317
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  A1S9; A1S9 protein; A1S9T and BN75 temperature sensitivity complementing; A1S9T; A1ST; GXP 1; GXP1; MGC4781; Protein A1S9; Uba1; UBA1_HUMAN; UBE 1 ; UBE 1X; UBE1; UBE1X; Ubiquitin activating enzyme E1; Ubiquitin-activating enzyme E1; Ubiquitin-like modier-activating enzyme 1.
• Also known as
  E1 Ubiquitin Activating Enzyme Antibody
• Other name
  Anti-E1 Ubiquitin Activating Enzyme
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Enzymes are cleaving the substrate. If the substrate is DNA they are called restriction enzymes. Activating enzymes will cut off the domain that is biological active to become functional.

• Gene target
  Ubiquitin   Activating  
• Gene symbol
  UBA6, UBA7, UBA5
• Short name
  Anti-E1 Ubiquitin Activating Enzyme
• Technique
  Enzyme, anti-, anti, antibody to, antibodies, enzymes
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  E1 Ubiquitin Activating Enzyme Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  enzymes, antibodies

Gene info

• Identity
  HGNC:25581
• Gene
  UBA6
• Long gene name
  ubiquitin like modifier activating enzyme 6
• Synonyms gene
  • UBE1L2
• Synonyms gene name
  • ubiquitin-activating enzyme E1-like 2
  • ubiquitin-like modifier activating enzyme 6
• Synonyms
  • FLJ10808
• Synonyms name
  • UBA6, ubiquitin-activating enzyme E1
• GenBank acession
  • AK094164
• Locus
  4q13.2
• Discovery year
  2006-02-14
• Entrez gene record
  55236
• Pubmed identfication
  • 17580310
• RefSeq identity
  • NM_018227
• Classification
  • Ubiquitin like modifier activating enzymes
• VEGA ID
  OTTHUMG00000129299

Gene info

• Identity
  HGNC:12471
• Gene
  UBA7
• Long gene name
  ubiquitin like modifier activating enzyme 7
• Synonyms gene
  • UBE1L
• Synonyms gene name
  • ubiquitin-activating enzyme E1-like
  • ubiquitin-like modifier activating enzyme 7
• Synonyms
  • D8
  • UBE2
  • UBA1B
• Synonyms name
  • UBA1, ubiquitin-activating enzyme E1 homolog B (yeast)
  • UBA7, ubiquitin-activating enzyme E1
• GenBank acession
  • BC006378
• Locus
  3p21.31
• Discovery year
  1993-11-24
• Entrez gene record
  7318
• Pubmed identfication
  • 8327486
• RefSeq identity
  • NM_003335
• Classification
  • Ubiquitin like modifier activating enzymes
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000158267

Gene info

• Identity
  HGNC:23230
• Gene
  UBA5
• Long gene name
  ubiquitin like modifier activating enzyme 5
• Synonyms gene
  • UBE1DC1
• Synonyms gene name
  • ubiquitin-activating enzyme E1-domain containing 1
  • ubiquitin-like modifier activating enzyme 5
• Synonyms
  • FLJ23251
• Synonyms name
  • UBA5, ubiquitin-activating enzyme E1 homolog (yeast)
• GenBank acession
  • AY253672
• Locus
  3q22.1
• Discovery year
  2003-10-28
• Entrez gene record
  79876
• Pubmed identfication
  • 11230166
  • 15071506
• RefSeq identity
  • NM_024818
• Classification
  • Ubiquitin like modifier activating enzymes
• VEGA ID
  OTTHUMG00000159759

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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