Ube2N Antibody, ALEXA FLUOR 594

• Catalog number
  bs-8351R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  Ube2N Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-Ube2N PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Ube2N
• Specificity
  This is a highly specific antibody against Ube2N.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Ube2N/UBC13
• Gene ID Number
  7334
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). UBC13, also known as UBE2N or BLU, is a 152 amino acid member of the E2 ubiquitin-conjugating enzyme family. Existing as a heterodimer with Mms2 (also known as UBE2V2), UBC13 catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. Additionally, UBC13 mediates the transcription of several target genes and is thought to play a role in cell cycle progression, cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  UBC 13; UBC13; UbCH ben; Ube 2N; Ube2n; UBE2N_HUMAN; ubiquitin carrier protein N; Ubiquitin conjugating enzyme E2 N; Ubiquitin conjugating enzyme E2N homologous to yeast UBC13; Ubiquitin conjugating enzyme E2N UBC13 homolog yeast; Ubiquitin conjugating enzyme E2N; ubiquitin protein ligase N; Ubiquitin-conjugating enzyme E2 N; ubiquitin-conjugating enzyme E2N homologous to yeast UBC13; ubiquitin-conjugating enzyme E2N UBC13 homolog yeast; Ubiquitin-protein ligase N; Yeast UBC13 homolog; bendless like ubiquitin conjugating enzyme; Bendless-like ubiquitin-conjugating enzyme; BLU; EC 6.3.2.19; Human epidermoid carcinoma mRNA for ubiquitin-conjugating enzyme E2 similar to Drosophila bendless gene product complete cds; MGC131857; MGC8489.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  Ube2N  
• Gene symbol
  UBE2N
• Short name
  Anti-Ube2N
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Ube2N Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  ubiquitin-conjugating enzyme E2N, HEL-S-71 and UBC13 and UbcH-ben and UbcH13 and UBCHBEN; UBC13, UBE2N and IDBG-51220 and ENSG00000177889 and 389898,7334, poly(A) RNA binding, nuclei, Ube2n and IDBG-187167 and ENSMUSG00000074781 and 102642334,93765, UBE2N and IDBG-630838 and ENSBTAG00000021767 and 541130

Gene info

• Identity
  HGNC:12492
• Gene
  UBE2N
• Long gene name
  ubiquitin conjugating enzyme E2 N
• Synonyms gene name
  • ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13)
  • ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)
  • ubiquitin-conjugating enzyme E2N
• Synonyms
  • UbcH-ben
  • UBC13
  • MGC8489
• GenBank acession
  • D83004
• Locus
  12q22
• Discovery year
  1997-04-16
• Entrez gene record
  7334
• Pubmed identfication
  • 8902611
• RefSeq identity
  • NM_003348
• Classification
  • Ubiquitin conjugating enzymes E2
• VEGA ID
  OTTHUMG00000170156

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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