TTF-1 / NKX2.1 (Thyroid & Lung Epithelial Marker) Mouse Monoclonal Antibody

  • Catalog number
    MBS438601
  • Price
    Please ask
  • Size
    5x0.1 mg (With BSA & Azide at 0.2mg/mL)
  • Products_type
    Antibody
  • Products_short_name
    [TTF-1 / NKX2.1]
  • Products_name_syn
    [BCH, Benign chorea, BHC, Homeobox protein Nkx2.1, NK2 homeobox 1, NKX2.1, NKX2A, TEBP, Thyroid nuclear factor-1, Thyroid specific enhancer binding protein, Thyroid transcription factor-1 (TTF-1), Tin man, TITF1, TTF-1]
  • Other_names
    [homeobox protein Nkx-2.1 isoform 1; Homeobox protein Nkx-2.1; homeobox protein Nkx-2.1; NK2 homeobox 1; Homeobox protein NK-2 homolog A; Thyroid nuclear factor 1; Thyroid transcription factor 1; TTF-1; Thyroid-specific enhancer-binding protein; T/EBP]
  • Products_gene_name
    [NKX2-1]
  • Other_gene_names
    [NKX2-1; NKX2-1; BCH; BHC; NK-2; TEBP; TTF1; NKX2A; NMTC1; T/EBP; TITF1; TTF-1; NKX2.1; TTF-1; T/EBP]
  • Clonality
    Monoclonal
  • Clone
    [8G7G3/1 + NX2.1/690]
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes a protein of 40kDa, identified as Thyroid transcription factor-1 (TTF-1). TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
  • Form
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
  • Storage_stability
    Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • Tested_application
    Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
  • Properties
    If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • About
    Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    NKX2-1, NKX2-1-AS1, TTF1, NKX2-2-AS1, RHOH, NKX2-8, NKX2-5, NKX2-4, NKX2-2, NKX2-6
  • Short name
    TTF-1 / NKX2 1 (Thyroid & Lung Epithelial ) Mouse Monoclonal Antibody
  • Technique
    Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Host
    Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG
  • Species
    Mouse, Mouses
  • Alternative name
    TTF-1 / NKX2.1 (Thyroid & Lung Epithelial detection labelled) Mouse monoclonal (antibody to-)
  • Alternative technique
    antibodies, murine
  • Tissue
    lung, thyroid
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    transcription termination factor 1
  • Synonyms gene name
    • transcription termination factor, RNA polymerase I
  • GenBank acession
  • Locus
  • Discovery year
    1996-05-13
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Myb/SANT domain containing
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    ras homolog family member H
  • Synonyms gene
  • Synonyms gene name
    • ras homolog gene family, member H
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1997-04-16
  • Entrez gene record
    399
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Rho family GTPases
  • VEGA ID
  • Locus Specific Databases
Gene info
  • Identity
  • Gene
  • Long gene name
    NK2 homeobox 8
  • Synonyms gene
  • Synonyms gene name
    • NK-2 homolog H (Drosophila)
    • NK2 transcription factor related, locus 8 (Drosophila)
  • Synonyms
  • Locus
  • Discovery year
    2002-07-08
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • NKL subclass homeoboxes and pseudogenes
  • VEGA ID
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    NK2 homeobox 4
  • Synonyms gene
  • Synonyms gene name
    • NK-2 (Drosophila) homolog D
    • NK2 transcription factor related, locus 4 (Drosophila)
  • Synonyms
  • Locus
  • Discovery year
    1992-06-12
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • NKL subclass homeoboxes and pseudogenes
  • VEGA ID
Gene info
  • Identity
  • Gene
  • Long gene name
    NK2 homeobox 2
  • Synonyms gene
  • Synonyms gene name
    • NK-2 (Drosophila) homolog B
    • NK2 transcription factor related, locus 2 (Drosophila)
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1992-06-12
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • NKL subclass homeoboxes and pseudogenes
  • VEGA ID
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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