anti-TrkA (phospho Ser791) Antibody
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Catalog number79-501
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PricePlease ask
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Size0.1 mg
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Gene infoRequired for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC γ1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC γ1-dependent signaling pathway.
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Gene namesMTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, MGF, SCF, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK1 transforming tyrosine kinase protein
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Antibodie s labelunlabelled serum
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PurityAntibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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Ab raised inRabbit
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TypePolyclonal
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Spicific toThis antibody detects endogenous level of TrkA only when phosphorylated at tyrosine 791.
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AntigenTrkA (Phospho-Ser791) antibody was made against a peptide sequence around phosphorylation site of tyrosine791 (P-V-Y (p) -L-D) derived from Human TrkA.
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Immuno applicationWestern Blot, immuno fluorescence
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Antibody adviceWestern Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
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Suspention pH azideAntibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Keep atStore antibody at -20 grades C for up to one year.
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Works withHuman
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Omim nr56118210
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Ncbi nrNP_001007793.1
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KDa140 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr4914
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GENE symbolNTRK1
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Antigene nameneurotrophic tyrosine kinase, receptor, type 1
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SourceHomo sapiens
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Protein nrP04629
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Short nameanti-TrkA (phospho Ser791) Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTrkA (phosphorilated Ser791) (antibody to-)
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Alternative techniqueantibodies
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MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data