anti-TrkA (phospho Ser791) Antibody

  • Catalog number
    79-501
  • Price
    Please ask
  • Size
    0.1 mg
  • Gene info
    Required for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC γ1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC γ1-dependent signaling pathway.
  • Gene names
    MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA, MGF, SCF, High affinity nerve growth factor receptor precursor, NTRK1, Slow nerve growth factor receptor, TRK1 transforming tyrosine kinase protein
  • Antibodie s label
    unlabelled serum
  • Purity
    Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Spicific to
    This antibody detects endogenous level of TrkA only when phosphorylated at tyrosine 791.
  • Antigen
    TrkA (Phospho-Ser791) antibody was made against a peptide sequence around phosphorylation site of tyrosine791 (P-V-Y (p) -L-D) derived from Human TrkA.
  • Immuno application
    Western Blot, immuno fluorescence
  • Antibody advice
    Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
  • Suspention pH azide
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Keep at
    Store antibody at -20 grades C for up to one year.
  • Works with
    Human
  • Omim nr
    56118210
  • Ncbi nr
    NP_001007793.1
  • KDa
    140 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    4914
  • GENE symbol
    NTRK1
  • Antigene name
    neurotrophic tyrosine kinase, receptor, type 1
  • Source
    Homo sapiens
  • Protein nr
    P04629
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    TrkA   phospho   Ser791  
  • Short name
    anti-TrkA (phospho Ser791) Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toTrkA (phosphorilated Ser791) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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