anti-TNPO3 Antibody

• Catalog number
  4599
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  TNPO3 Antibody: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.
• Gene names
  TNPO3 Antibody: IPO12, TRNSR, LGMD1F, MTR10A, TRN-SR, TRN-SR2, IPO12, Transportin-3, Importin-12, Imp12
• Antibodie s label
  unlabelled serum
• Purity
  TNPO3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TNPO3 antibody was made against a 18 amino acid synthetic peptide from near the amino terminus of human TNPO3.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  TNPO3 antibody can be used for detection of TNPO3 by Western blot at 1 - 2 ug/mL.
• Suspention pH azide
  TNPO3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  TNPO3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  119604114
• Ncbi nr
  EAW83708
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  23534
• GENE symbol
  TNPO3
• Antigene name
  transportin 3
• Source
  Homo sapiens
• Protein nr
  Q9Y5L0
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TNPO3  
• Gene symbol
  TNPO3
• Short name
  anti-TNPO3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTNPO3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17103
• Gene
  TNPO3
• Long gene name
  transportin 3
• Synonyms gene
  • LGMD1F
• Synonyms gene name
  • limb girdle muscular dystrophy 1F (autosomal dominant)
• Synonyms
  • TRN-SR
  • MTR10A
  • TRN-SR2
  • IPO12
• Synonyms name
  • importin 12
• GenBank acession
  • AF145029
• Locus
  7q32.1
• Discovery year
  2003-12-09
• Entrez gene record
  23534
• Pubmed identfication
  • 10366588
  • 10713112
  • 23543484
  • 23667635
• RefSeq identity
  • NM_012470
• Classification
  • Importins
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000158409

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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