TNIK (Ser764) Antibody, ALEXA FLUOR 594

• Catalog number
  bs-5598R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  TNIK (Ser764) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-TNIK Ser764 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TNIK Ser764
• Specificity
  This is a highly specific antibody against TNIK Ser764.
• Modification
  Phosphorylation
• Modification Site
  Ser764
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  759-766/1360
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human TNIK around the phosphorylation site of Ser764
• Gene ID Number
  23043
• Swiss Prot
  Q9UKE5
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  TRAF2 and NCK-interacting protein kinase; TNIK; KIAA0551
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  TNIK   Ser764  
• Gene symbol
  TNIK
• Short name
  Anti-TNIK Ser764
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  TNIK (Ser764) Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  TRAF2 and NCK interacting kinase, TNIK and IDBG-64741 and ENSG00000154310 and 23043, transferase activity, nuclei, Tnik and IDBG-134833 and ENSMUSG00000027692 and 665113, TNIK and IDBG-636319 and ENSBTAG00000011742 and 539627

Gene info

• Identity
  HGNC:30765
• Gene
  TNIK
• Long gene name
  TRAF2 and NCK interacting kinase
• Synonyms
  • KIAA0551
• GenBank acession
  • AF172264
• Locus
  3q26.2-q26.31
• Discovery year
  2004-02-26
• Entrez gene record
  23043
• Pubmed identfication
  • 9628581
  • 10521462
• RefSeq identity
  • NM_015028
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159036

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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