TLR7 Antibody

• Catalog number
  3557-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  TLR7
• Target Alternative Name
  TLR7 , Anti-TLR7 , PRO285 , UNQ248
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 468 of human TLR7
• Accession
  AAZ99026
• Gene Id
  74096726
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  100 µl affinity purified rabbit anti-TLR7 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (1:500-1000 dilution). However, the optimal conditions should be determined individually. Ramos cell lysate can be used as a positive control.
• Description
  The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and sμggests that these receptors are involved in mediating inflammatory responses. TLR6 and TLR7 induce NFkB signaling upon activation, sμggesting they play a role in immune reponse. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR7  
• Gene symbol
  TLR7
• Short name
  TLR7 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  toll-like receptor 7 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 7, TLR7 and IDBG-44230 and ENSG00000196664 and 51284, siRNA binding, Plasma membranes, Tlr7 and IDBG-185532 and ENSMUSG00000044583 and 170743, TLR7 and IDBG-639302 and ENSBTAG00000022161 and 493686

Gene info

• Identity
  HGNC:15631
• Gene
  TLR7
• Long gene name
  toll like receptor 7
• Synonyms gene name
  • toll-like receptor 7
• GenBank acession
  • AF240467
• Locus
  Xp22.2
• Discovery year
  2001-04-27
• Entrez gene record
  51284
• Pubmed identfication
  • 11022119
• RefSeq identity
  • NM_016562
• Classification
  • Toll like receptors
• VEGA ID
  OTTHUMG00000021137
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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