anti-TLR6 Antibody
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Catalog number3651
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTLR6 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identify. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 dimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but also can lead to apoptotic responses.
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Gene namesTLR6 Antibody: CD286, Toll-like receptor 6
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Antibodie s labelunlabelled serum
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PurityTLR6 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTLR6 antibody was made against a peptide corresponding to 15 amino acids near the amino terminus of human TLR6.
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Immuno applicationELISA, Western Blot, immuno-cyto-chemistry
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Antibody adviceTLR6 antibody can be used for detection of TLR6 by Western blot at 0.5 to 2 ug/mL. Antibody can also be used for immunocytochemistry starting at 10 ug/mL.
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Suspention pH azideTLR6 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTLR6 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse
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Omim nr20143971
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Ncbi nrNP_006059
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr10333
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GENE symbolTLR6
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Antigene nametoll-like receptor 6
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SourceHomo sapiens
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Protein nrQ9Y2C9
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTLR6
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Short nameanti-TLR6 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTLR6 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targettoll-like receptor 6, CD286, TLR6 and IDBG-13675 and ENSG00000174130 and 10333, lipopeptide binding, Plasma membranes, Tlr6 and IDBG-165921 and ENSMUSG00000051498 and 21899, BT.45021 and IDBG-641606 and ENSBTAG00000014031 and 407237
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Gene info
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Identity
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Gene
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Long gene nametoll like receptor 6
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Synonyms gene name
- toll-like receptor 6
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Synonyms
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Locus
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Discovery year2001-10-01
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Entrez gene record
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Pubmed identfication
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Classification
- Toll like receptors
- CD molecules
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data