TLR2 Antibody

• Catalog number
  3552R-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  TLR2
• Target Alternative Name
  TLR2 , Anti-TLR2 , CD282 , TIL4, Toll-like receptor 2
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat, monkey
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 753 of mouse TLR2
• Accession
  AAH14693
• Gene Id
  24088
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~86 kDa TLR2 in Jurkat cell lysate. Reactivity to other species has not been tested. Blocking peptide (Cat.# 3552RBP-50) is available separately.
• Description
  The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types is regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TLR2  
• Gene symbol
  TLR2
• Short name
  TLR2 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  toll-like receptor 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  toll-like receptor 2, CD282 and TIL4, TLR2 and IDBG-41789 and ENSG00000137462 and 7097, lipopeptide binding, Cell surfaces, Tlr2 and IDBG-154818 and ENSMUSG00000027995 and 24088, TLR2 and IDBG-629032 and ENSBTAG00000008008 and 281534

Gene info

• Identity
  HGNC:11848
• Gene
  TLR2
• Long gene name
  toll like receptor 2
• Synonyms gene name
  • toll-like receptor 2
• Synonyms
  • TIL4
  • CD282
• GenBank acession
  • U88878
• Locus
  4q31.3
• Discovery year
  1998-06-25
• Entrez gene record
  7097
• Pubmed identfication
  • 9435236
• Classification
  • Toll like receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000161525

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products