anti-TIRAP Antibody
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Catalog number3155
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoTIRAP Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate various kinases and transcription factors. In TIRAP-deficient mice, TLR signaling in response to TLR2 ligands (using either TLR1 and TLR6 as co-receptors) is totally abolished, suggesting that MyD88 and TIRAP work together and are both required for TLR2 signaling. Furthermore, these mice are also resistant to the toxic effects of LPS and show defects in NF-kB and MAP kinase activation, suggesting that TIRAP is also involed in TLR4 signaling.
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Gene namesTIRAP Antibody: Mal, wyatt, BACTS1, MyD88-2, MAL, Adaptor protein Wyatt, TIR domain-containing adapter protein
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Antibodie s labelunlabelled serum
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PurityTIRAP Antibody is Ion exchange chromatography purified.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenTIRAP antibody was made against a peptide corresponding to amino acids near the middle of human TIRAP.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody adviceTIRAP antibody can be used for detection of TIRAP by Western blot at 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 20 ug/mL. For immunofluorescence start at 2 ug/mL.
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Suspention pH azideTIRAP Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atTIRAP antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman
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Omim nr15705407
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Ncbi nrAAL05627
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr114609
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GENE symbolTIRAP
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Antigene nametoll-interleukin 1 receptor (TIR) domain containing adaptor protein
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SourceHomo sapiens
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Protein nrP58753
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolTIRAP
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Short nameanti-TIRAP Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toTIRAP (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targettoll-interleukin 1 receptor (TIR) domain containing adaptor protein, TIRAP and IDBG-75811 and ENSG00000150455 and 114609, phosphatidylinositol-4, Plasma membranes, Tirap and IDBG-148134 and ENSMUSG00000032041 and 117149, TIRAP and IDBG-642760 and ENSBTAG00000021504 and 531079
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Gene info
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Identity
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Gene
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Long gene nameTIR domain containing adaptor protein
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Synonyms gene name
- Toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-06-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TIR domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
