anti-TAZ Antibody

• Catalog number
  79-735
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation. Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex. Regulates embryonic stem-cell self-renewal, promotes cell proliferation and epithelial-mesenchymal transition.
• Gene names
  TAZ, WWTR1
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of total TAZ protein.
• Antigen
  TAZ antibody was made against a peptide sequence around aa.386~390 (V-E-S-A-L) derived from Human TAZ.
• Immuno application
  Western Blot
• Antibody advice
  Western Blot: 1:500~1:1000
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  270132693
• Ncbi nr
  NP_001161750.1
• KDa
  49 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  25937
• GENE symbol
  WWTR1
• Antigene name
  WW domain containing transcription regulator 1
• Source
  Homo sapiens
• Protein nr
  Q9GZV5
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TAZ  
• Gene symbol
  WWTR1, ZBTB18, TAFAZZIN
• Short name
  anti-TAZ Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTAZ (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:24042
• Gene
  WWTR1
• Long gene name
  WW domain containing transcription regulator 1
• Synonyms
  • TAZ
  • DKFZp586I1419
• Synonyms name
  • transcriptional coactivator with PDZ-binding motif
• GenBank acession
  • AK022036
• Locus
  3q25.1
• Discovery year
  2004-12-03
• Entrez gene record
  25937
• Pubmed identfication
  • 11118213
  • 15096513
• RefSeq identity
  • NM_015472
• VEGA ID
  OTTHUMG00000159614

Gene info

• Identity
  HGNC:13030
• Gene
  ZBTB18
• Long gene name
  zinc finger and BTB domain containing 18
• Synonyms gene
  • ZNF238
• Synonyms gene name
  • zinc finger protein 238
• Synonyms
  • C2H2-171
  • TAZ-1
  • RP58
• GenBank acession
  • U38896
• Locus
  1q44
• Discovery year
  1998-11-19
• Entrez gene record
  10472
• Pubmed identfication
  • 9568537
  • 9013868
• RefSeq identity
  • NM_205768
• Classification
  • BTB domain containing
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000040013

Gene info

• Identity
  HGNC:11577
• Gene
  TAFAZZIN
• Long gene name
  tafazzin, phospholipid-lysophospholipid transacylase
• Synonyms gene
  • CMD3A
  • EFE2
  • EFE
  • TAZ
• Synonyms gene name
  • endocardial fibroelastosis 2
  • cardiomyopathy, dilated 3A (X-linked)
  • tafazzin
• Synonyms
  • BTHS
  • G4.5
  • TAZ1
• Synonyms name
  • Barth syndrome
• GenBank acession
  • X92762
• Locus
  Xq28
• Discovery year
  1989-05-29
• Entrez gene record
  6901
• Pubmed identfication
  • 8042670
• VEGA ID
  OTTHUMG00000033190
• Locus Specific Databases
  • TAZbase: Mutation registry for Barth syndrome
  • LRG_131

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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