TAF1 polyclonal antibody
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Catalog number6845-50
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PricePlease ask
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Size50 μl
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Antibody TargetTAF1
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Target Alternative NameTAF (II) 250, TBP-associated factor 250 kDa, p250, BA2R, CCG1, CCGS, TAF2A
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Antibody TypePolyclonal
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Species ReactivitiesHuman.
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Immunogen SequencePolyclonal antibody raised in rabbit against human TAF1 (TATA box binding protein (TBP)-associated factor; Transcription initiation factor TFIID subunit 1), using the recombinant double bromodomain module of the protein.
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AccessionP21675
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Gene Id6872
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS with 0.05% (W/V) sodium azide.
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PurificationWhole Anti-Sera
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ApplicationWestern blot
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Positive ControlWestern blot: HeLa cells
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Application And UsagesWestern Blot: 1:1000.
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DescriptionTAF1 is the largest component and core scaffold of the TFIID basal transcription factor complex which also includes TBP. The protein is able to auto phosphorylate or trans phosphorylate other transcription factors such as TP53 on ‘Thr-55’, leading to MDM2-mediated degradation of TP53, and GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Dot Blot VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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French translationanticorps
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Gene target
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Gene symbolTAF1
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Short nameTAF1 polyclonal antibody
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TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeRabbit IgG
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Alternative nameTAF1 polyclonal (antibody to-)
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene nameTATA-box binding protein associated factor 1
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Synonyms gene
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Synonyms gene name
- TATA box binding protein (TBP)-associated factor, RNA polymerase II, A, 250kD
- dystonia 3 (with Parkinsonism)
- TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
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Synonyms
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- General transcription factor IID complex subunits
- Lysine acetyltransferases
- Bromodomain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data