SUV39H1 Antibody, ALEXA FLUOR 488

  • Catalog number
    bs-5708R-A488
  • Price
    Please ask
  • Size
    100ul
  • Long name
    SUV39H1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
  • Also known as
    Anti-SUV39H1 PAb ALEXA FLUOR 488
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 488
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SUV39H1
  • Specificity
    This is a highly specific antibody against SUV39H1.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Subcellular location
    Nucleus
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1
  • Gene ID Number
    6839
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    499nm/519nm
  • Synonyms
    H3 K9 HMTase; H3 K9 HMTase1; H3-K9-HMTase 1; Histone H3 K9 methylation; Histone H3 Lys 9 methylation; Histone H3-K9 methyltransferase 1; Histone H3-K9 methyltransferase1; Histone lysine N methyltransferase H3 lysine 9 specic 1; Histone lysine N methyltransferase, H3 lysine 9 specic 1; Histone-lysine N-methyltransferase SUV39H1; KMT1 A; Lysine N methyltransferase 1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; Suvar3 9 homolog 1; Suvar3-9 homolog 1; Suppressor of variegation 3 9 homolog 1 Drosophila; Suppressor of variegation 3-9 homolog 1; SUV39 H1; SUV39H; SUV39H1; SUV91_HUMAN.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-SUV39H1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor
  • French translation
    anticorps
  • Gene target
    SUV39H1  
  • Gene symbol
    SUV39H1
  • Short name
    Anti-SUV39H1
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 488
  • Alternative name
    SUV39H1 Polyclonal Antibody, ALEXA FLUOR 488
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    SUV39H1 histone lysine methyltransferase
  • Synonyms gene
  • Synonyms gene name
    • suppressor of variegation 3-9 (Drosophila) homolog 1
    • suppressor of variegation 3-9 homolog 1 (Drosophila)
    • suppressor of variegation 3-9 homolog 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1996-04-12
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • eNoSC complex
    • SET domain containing
    • Lysine methyltransferases
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee