anti-Stat5 Antibody

anti-Stat5 Antibody is available 1 time from Biovision labs

3472-100 | anti-Stat5 Antibodysize: Stat5 Antibody | 369.94 USD

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  • Target of this antibody:
    STAT5
  • Alternative names of antibody target:
    Signal transducer and activator of transcription 5, stat -5, STAT5, STAT-5, STAT 5
  • Background information:
    Membrane receptor signaling by various ligands induces activation of Jak kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Althoμgh early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 is activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
  • Antibody host:
    Rabbit
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • This antibody reacts with:
    Human, mouse, rat
  • Immunogene sequence:
    Synthetic peptide surrounding amino acid 777 of human Stat5
  • Concentration of antibody:
    0.5 mg/ml
  • Form of antibody:
    Liquid
  • Formulation of this antibody:
    100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS).
  • Purification method:
    Affinity purified
  • This antibody has been succesfully tested for use in following methods:
    Western blot, Immunoprecipitation, Immunohistochemistry
  • Recommended usage:
    Western blotting (2-10 µg/ml), immunoprecipitation (20 µg/ml) and Immunohistochemistry (5 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~95 kDa Stat5 of human, mouse and rat origins. Reactivity to other species has not been tested.
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    anti-Stat5 Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-Stat5 (Antibody to)
  • Alternative technique
    antibodies
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