anti-PILRB Antibody

• Catalog number
  26-179
• Price
  Please ask
• Size
  50 ug

• Gene info
  Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.Cell signaling pathways rely on a dynamic interaction between activating and inhibiting processes. SHP-1-mediated dephosphorylation of protein tyrosine residues is central to the regulation of several cell signaling pathways. Two types of inhibitory receptor superfamily members are immunoreceptor tyrosine-based inhibitory motif (ITIM)-bearing receptors and their non-ITIM-bearing, activating counterparts. Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This particular gene encodes the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. Alternative splicing has been observed at this locus and three variants, encoding two distinct isoforms, are described. Additional transcript variants have been identified but their full-length nature has not been determined.
• Gene names
  PILRB, FDFACT1, FDFACT2
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PILRB.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  PILRB antibody can be used for detection of PILRB by ELISA at 1:312500. PILRB antibody can be used for detection of PILRB by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PILRB antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  30179915
• Ncbi nr
  NP_038468
• KDa
  23 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  29990
• GENE symbol
  PILRB
• Antigene name
  paired immunoglobin-like type 2 receptor beta
• Source
  Homo sapiens
• Protein nr
  Q9UKJ0
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PILRB  
• Gene symbol
  PILRB, STAG3L5P-PVRIG2P-PILRB
• Short name
  anti-PILRB Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPILRB (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18297
• Gene
  PILRB
• Long gene name
  paired immunoglobin like type 2 receptor beta
• Synonyms gene name
  • paired immunoglobin-like type 2 receptor beta
• Synonyms
  • FDFACT1
  • FDFACT2
• GenBank acession
  • AF161081
  • AJ400845
• Locus
  7q22.1
• Discovery year
  2003-09-10
• Entrez gene record
  29990
• Pubmed identfication
  • 10660620
• RefSeq identity
  • NM_178238
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000155363

Gene info

• Identity
  HGNC:48898
• Gene
  STAG3L5P-PVRIG2P-PILRB
• Long gene name
  STAG3L5P-PVRIG2P-PILRB readthrough
• Locus
  7q22.1
• Discovery year
  2013-06-26
• Entrez gene record
  101752399
• VEGA ID
  OTTHUMG00000186252

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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