anti-SP1 (phospho Thr739) Antibody
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Catalog number
79-481
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Price
Please ask
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Size
0.1 mg
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Gene info
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
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Gene names
TSFP1, TSFP1, Sp1 transcription factor
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Antibodie s label
unlabelled serum
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Purity
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
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Ab raised in
Rabbit
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Type
Polyclonal
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Spicific to
This antibody detects endogenous levels of SP1 only when phosphorylated at threonine 739.
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Antigen
SP1 (Phospho-Thr739) antibody was made against a peptide sequence around phosphorylation site of threonine 739 (T-A-T (p) -P-S) derived from human SP1 .
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Immuno application
Western Blot
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Antibody advice
Western Blot: 1:500~1:1000
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Suspention pH azide
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Keep at
Store antibody at -20 grades C for up to one year.
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Works with
Human, Rat
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Omim nr
38372901
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Ncbi nr
NP_612482.2
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KDa
90 kDa
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
6667
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GENE symbol
SP1
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Antigene name
Sp1 transcription factor
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Source
Homo sapiens
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Protein nr
P08047
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
SP1, PRSS55, ST14
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Short name
anti-SP1 (phospho Thr739) Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody toSP1 (phosphorilated Thr739) (antibody to-)
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
Sp1 transcription factor
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1991-06-04
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Entrez gene record
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Pubmed identfication
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Classification
- Sp transcription factors
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
serine protease 55
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Synonyms gene name
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Synonyms
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GenBank acession
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Locus
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Discovery year
2010-04-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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