SODD Antibody

• Catalog number
  3221-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  SODD
• Target Alternative Name
  silencer of death domains, BAG family molecular chaperone regulator 4; BAG-4; Bcl-2-associated athanogene 4; Silencer of death domains
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide mapping to the N-terminus of human SODD
• Accession
  NP_004865
• Gene Id
  9530
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) peptide affinity purified, rabbit anti-SODD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blot analysis (1-2 µg/ml). However, the optimal conditions should be determined individually. The antibody detects an approximately 60 kDa human SODD by Western blot analysis. HeLa and THP-1 cell lysate can be used as positive control.
• Description
  Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family throμgh their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules throμgh the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domain. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SODD  
• Gene symbol
  BAG4
• Short name
  SODD Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  SODD (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:940
• Gene
  BAG4
• Long gene name
  BAG cochaperone 4
• Synonyms gene name
  • BCL2 associated athanogene 4
• Synonyms
  • SODD
• Synonyms name
  • silencer of death domains
• GenBank acession
  • AF095194
• Locus
  8p11.23
• Discovery year
  1999-04-23
• Entrez gene record
  9530
• Pubmed identfication
  • 9873016
  • 9915703
• RefSeq identity
  • NM_004874
• Classification
  • BAG cochaperones
• VEGA ID
  OTTHUMG00000164064

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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