SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1) Antibody

  • Catalog number
    MBS626954
  • Price
    Please ask
  • Size
    100ug
  • Alternative name1
    Anti-SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1)
  • Alternative name2
    SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1)
  • Alternative name3
    SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1)
  • Alternative name4
    SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase
  • Alternative name5
    Anti -SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT-induced STAT inhibitor, SSI-1)
  • Other names
    suppressor of cytokine signaling 3; Suppressor of cytokine signaling 3; suppressor of cytokine signaling 3; STAT-induced STAT inhibitor 3; cytokine-inducible SH2 protein 3; suppressor of cytokine signaling 3; Cytokine-inducible SH2 protein 3; CIS-3; STAT-induced STAT inhibitor 3
  • Gene name
    N/A
  • Gene name synonims
    N/A
  • Other gene names
    SOCS3; SOCS3; CIS3; SSI3; ATOD4; Cish3; SSI-3; SOCS-3; CIS3; SSI3; SOCS-3; CIS-3; SSI-3
  • Category
    Antibodies
  • Clonality
    Polyclonal
  • Immunoglobulin isotype
    IgG
  • Clone
    Polyclonal antibody
  • Host organism
    Host: Rabbit; Source: Human
  • Species reactivity
    Human, Mouse
  • Specificity and cross reactivity
    Recognizes the human SOCS-1 protein at ~30kD. Species Crossreactivity
  • Purification method
    Affinity Purified by immunoaffinity chromatography.
  • Form Appearance
    Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
  • Concentration
    N/A
  • Storage and shipping
    Store at 4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, productone should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested for
    Western Blot (WB)
  • Description
    productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
  • Advisory
    In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    If you buy Antibodies supplied by MBS Polyclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Additional description
    Cytokines and Chemokines are chemotaxis related small proteins between 5 to 20 kDa. Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
  • French translation
    anticorps
  • Gene target
    SOCS   Suppressor   Cytokine   Signalling   Janus   kinase   JAK   binding   protein   STAT   STAT   inhibitor   SSI-1  
  • Gene symbol
    SOCS1, STAT6, SOAT1, SOCS3, SOCS2, CISH, JAK3, SOCS5, IGHVII-1-1, MIR1-1
  • Short name
    SOCS 1(Suppressor of Cytokine Signalling 1, Janus kinase (JAK) binding protein, STAT- STAT inhibitor, SSI-1) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative name
    SOCS 1(Suppressor on Cytokine Signalling 1, Janus phosphorylation catalyst (JAK) binding protein, Signal transducer and activation on transcription-induced Signal transducer and activation on transcription suppressor, SSI-1) (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:5670
  • Gene
    IGHVII-1-1
  • Long gene name
    immunoglobulin heavy variable (II)-1-1 (pseudogene)
  • Synonyms gene name
    • immunoglobulin heavy variable (II)-1-1
    • immunoglobulin heavy variable (II)-1-1 pseudogene
  • Synonyms
  • GenBank acession
  • Locus
    14q32.33
  • Discovery year
    2000-04-17
  • Entrez gene record
    28377
  • RefSeq identity
  • Classification
    • Immunoglobulin heavy locus at 14q32.33
  • VEGA ID
    OTTHUMG00000152325
Gene info
MeSH Data
  • Name
    Blotting, Western
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Similar products
PathwayReady JAK / STAT Signaling Inhibitor Panel
Catalog number: MBS843024
Size: 8 Inhibitors
Price: Please ask
Filters
SOCS 1 Suppressor of Cytokine Signalling 1 Janus kinase JAK
Contact
Back
Chat with gentaur.com employee