anti-SMC1 (phospho Ser957) Antibody

• Catalog number
  79-193
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
• Gene names
  SMC1, SMCB, CDLS2, SB1.8, SMC1L1, DXS423E, SMC1alpha, APRF, SM1A, SMC1A, SMC1 alpha protein
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of SMC1 only when phosphorylated at serine 957.
• Antigen
  SMC1 (Phospho-Ser957) antibody was made against a peptide sequence around phosphorylation site of serine 957 (G-S-S (p) -Q-G) derived from Human SMC1.
• Immuno application
  Western Blot, immuno-histo-chemistry
• Antibody advice
  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse
• Omim nr
  30581135
• Ncbi nr
  NP_006297.2
• KDa
  145 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  8243
• GENE symbol
  SMC1A
• Antigene name
  structural maintenance of chromosomes 1A
• Source
  Homo sapiens
• Protein nr
  Q14683
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SMC1   phospho   Ser957  
• Short name
  anti-SMC1 (phospho Ser957) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSMC1 (phosphorilated Ser957) (antibody to-)
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products