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Gene info
Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. SLC13A3 represents the high-affinity form.Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet.
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Gene names
SLC13A3, NADC3, SDCT2
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Antibodie s label
unlabelled serum
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Purity
Antibody is purified by protein A chromatography method.
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Ab raised in
Rabbit
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Type
Polyclonal
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Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC13A3.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry
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Antibody advice
SLC13A3 antibody can be used for detection of SLC13A3 by ELISA at 1:312500. SLC13A3 antibody can be used for detection of SLC13A3 by western blot at 2.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Suspention pH azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
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Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store SLC13A3 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
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Works with
Human
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Omim nr
58761541
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Ncbi nr
NP_001011554
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KDa
61 kDa, 67 kDa
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Vial with antibody
Lyophilized
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Quantity per ml
1 mg/ml
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NCBI GENE nr
64849
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GENE symbol
SLC13A3
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Antigene name
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
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Source
Homo sapiens
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Protein nr
Q8WWT9
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
SLC13A3
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Short name
anti-SLC13A3 Antibody
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Technique
Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative name
Antibody tosolute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, SLC13A3 and IDBG-79300 and ENSG00000158296 and 64849, dicarboxylate symporter activity, Plasma membranes, Slc13a3 and IDBG-212716 and ENSMUSG00000018459 and 114644, BT.26578 and IDBG-643088 and ENSBTAG00000000873 and 526291
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