SHFM3 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-8390R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  SHFM3 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-SHFM3 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  SHFM3
• Specificity
  This is a highly specific antibody against SHFM3.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHFM3
• Gene ID Number
  6468
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) . SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  DAC; Dactylin; F box and WD 40 domain containing protein 4; F box and WD 40 domain protein 4; F box and WD repeat domain containing 4; F box/WD repeat containing protein 4; F box/WD repeat protein 4; F-box and WD-40 domain-containing protein 4; F-box/WD repeat-containing protein 4; FBW 4; FBW4; FBWD 4; FBWD4; FBXW 4; FBXW4; FBXW4_HUMAN; SHFM 3; SHSF 3; SHSF3; Split hand/foot malformation ectrodactyly type.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  SHFM3  
• Gene symbol
  FBXW4
• Short name
  Anti-SHFM3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  SHFM3 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10847
• Gene
  FBXW4
• Long gene name
  F-box and WD repeat domain containing 4
• Synonyms gene
  • SHFM3
• Synonyms gene name
  • split hand/foot malformation (ectrodactyly) type 3
  • F-box and WD-40 domain protein 4
• Synonyms
  • Fbw4
  • dactylin
• GenBank acession
  • AF281859
• Locus
  10q24.32
• Discovery year
  1994-09-26
• Entrez gene record
  6468
• Pubmed identfication
  • 8723077
  • 7912888
• RefSeq identity
  • NM_022039
• Classification
  • WD repeat domain containing
  • F-box and WD repeat domain containing
• VEGA ID
  OTTHUMG00000018938

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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