anti-SCO2 Antibody

• Catalog number
  4045
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SCO2 Antibody: Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.
• Gene names
  SCO2 Antibody: SCOD1, Protein SCO2 homolog, mitochondrial
• Antibodie s label
  unlabelled serum
• Purity
  SCO2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  SCO2 antibody was made against a 19 amino acid synthetic peptide from near the carboxy terminus of human SCO2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  SCO2 antibody can be used for detection of SCO2 by Western blot at 0.5 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  SCO2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SCO2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  8134662
• Ncbi nr
  O43819
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  6341
• GENE symbol
  SCO1
• Antigene name
  SCO cytochrome oxidase deficient homolog 1 (yeast)
• Source
  Homo sapiens
• Protein nr
  O43819
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SCO2  
• Gene symbol
  SCO2
• Short name
  anti-SCO2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSCO2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10604
• Gene
  SCO2
• Long gene name
  synthesis of cytochrome C oxidase 2
• Synonyms gene
  • MYP6
• Synonyms gene name
  • SCO (cytochrome oxidase deficient, yeast) homolog 2
  • SCO cytochrome oxidase deficient homolog 2 (yeast)
  • myopia 6
  • SCO2, cytochrome c oxidase assembly protein
  • SCO cytochrome c oxidase assembly protein 2
• Synonyms
  • SCO1L
• GenBank acession
  • AL021683
• Locus
  22q13.33
• Discovery year
  1999-10-12
• Entrez gene record
  9997
• Pubmed identfication
  • 10218584
  • 16091356
  • 23643385
• RefSeq identity
  • NM_005138
• Classification
  • Mitochondrial respiratory chain complex assembly factors
• VEGA ID
  OTTHUMG00000191637

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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