Anti-SCN1B (Polyclonal), ALEXA Fluor 594

  • Catalog number
    GENTObs-6687R-A594
  • Price
    Please ask
  • Size
    100 microliters
  • Type
    Conjugated Primary Antibody
  • Conjugated with
    ALEXA FLUOR® 594
  • Host organism
    Rabbit (Oryctolagus cuniculus)
  • Target Protein Peptide
    SCN1B
  • Specificity
    This antibody reacts specifically with SCN1B
  • Modification
    No modification has been applied to this antibody
  • Modification site
    None
  • Clonality
    Polyclonal Antibody
  • Clone
    Polyclonal Antibodies
  • Concentration
    1ug per 1ul
  • Subcellular locations
    Extracellular
  • Antigen Source
    KLH conjugated synthetic peptide derived from human SCN1B
  • Gene ID
    6324
  • Swiss Prot
    N/A
  • Applications
    FCM, IF(IHC-P)
  • Applications with corresponding dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200)
  • Cross reactive species
    Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
  • Cross Reactive Species details
    No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
  • Background information
    Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-1 can modulate multiple alpha subunit isoforms from brain, skeletal muscle, and heart. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.Tissue specificity; Abundantly expressed in skeletal muscle, heart and brain.
  • Purification method
    Purified by Protein A.
  • Storage
    Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
  • Excitation emission
    590nm/617nm
  • Synonyms
    GEFSP1; SCN1B; SCN1B_HUMAN; sodium channel beta 1 subunit; Sodium channel subunit beta 1; Sodium channel subunit beta-1; Sodium channel voltage gated type I beta.
  • Also known as
    SCN1B Polyclonal Antibody
  • Other name
    Anti-SCN1B Polyclonal
  • Advisory
    Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Properties
    For facs or microscopy Alexa 1 conjugate.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR® 594
  • Conjugated
    Alexa conjugate 1
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Group
    Polyclonals and antibodies
  • About
    Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
  • Gene target
    SCN1B  
  • Gene symbol
    SCN1B
  • Short name
    Anti-SCN1B
  • Technique
    Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 594
  • Alternative name
    SCN1B Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
  • Alternative technique
    polyclonals, antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    sodium voltage-gated channel beta subunit 1
  • Synonyms gene name
    • sodium channel, voltage-gated, type I, beta polypeptide
    • sodium channel, voltage-gated, type I, beta
    • sodium channel, voltage-gated, type I, beta subunit
    • sodium channel, voltage gated, type I beta subunit
  • Locus
  • Discovery year
    1990-05-14
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Sodium voltage-gated channel beta subunits
    • V-set domain containing
  • VEGA ID
  • Locus Specific Databases
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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