anti-TRDMT1 Antibody

• Catalog number
  26-329
• Price
  Please ask
• Size
  50 ug

• Gene info
  CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. TRDMT1 is a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome.CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Gene names
  TRDMT1, DNMT2, M.HsaIIP, PuMet, RNMT1, DMNT2, PUMET, MHSAIIP
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRDMT1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  TRDMT1 antibody can be used for detection of TRDMT1 by ELISA at 1:312500. TRDMT1 antibody can be used for detection of TRDMT1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store TRDMT1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  4758184
• Ncbi nr
  NP_004403
• KDa
  44 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  1787
• GENE symbol
  TRDMT1
• Antigene name
  tRNA aspartic acid methyltransferase 1
• Source
  Homo sapiens
• Protein nr
  O14717
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  TRDMT1  
• Gene symbol
  TRDMT1
• Short name
  anti-TRDMT1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTRDMT1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2977
• Gene
  TRDMT1
• Long gene name
  tRNA aspartic acid methyltransferase 1
• Synonyms gene
  • DNMT2
• Synonyms gene name
  • DNA (cytosine-5-)-methyltransferase 2
• Synonyms
  • RNMT1
• Synonyms name
  • tRNA (cytosine(38)-C(5))-methyltransferase
• GenBank acession
  • AJ223333
• Locus
  10p13
• Discovery year
  1998-05-07
• Entrez gene record
  1787
• Pubmed identfication
  • 9425235
  • 9763678
  • 16424344
• RefSeq identity
  • NM_004412
• Classification
  • 7BS C5-cytosine DNA/RNA methyltransferases
• VEGA ID
  OTTHUMG00000017745

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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