Anti-RAT MDM2

  • Catalog number
    MBS220632
  • Price
    Please ask
  • Size
    1 mililiter
  • Alternative name1
    Anti-RABBIT ANTI RAT MDM2
  • Alternative name2
    RABBIT ANTI RAT MDM2
  • Alternative name3
    Lapin ANTI Rattus norvegicus MDM2
  • Alternative name4
    MDM2
  • Alternative name5
    N/A
  • Other names
    N/A
  • Gene name
    MDM2
  • Gene name synonims
    N/A
  • Other gene names
    N/A
  • Category
    Antibodies
  • Clonality
    Polyclonal
  • Immunoglobulin isotype
    Polyclonal IgG
  • Clone
    Polyclonal antibody
  • Host organism
    Rabbit
  • Species reactivity
    Rat
  • Specificity and cross reactivity
    MDM2 This item is recognizes rat MDM2, a nuclear phosphoprotein that controls intracellular levels of the tumour suppressor protein p53 by ubiquitination and subsequent proteasomal degradation. MDM2 also interacts with the retinoblastoma (RB) protein and E2F-1, to promote G1-S phase transition in the cell cycle.
  • Purification method
    N/A
  • Form Appearance
    Purified (Purified IgG - liquid)
  • Concentration
    IgG concentration 5.0 mg/ml
  • Storage and shipping
    Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
  • Tested for
    ELISA (EIA)
  • Description
    productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
  • Advisory
    In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
  • Additional description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • About
    Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
  • Latin name
    Rattus norvegicus
  • Gene target
    MDM2  
  • Gene symbol
    MDM2
  • Short name
    Anti- MDM2
  • Technique
    anti-, anti, antibody to, antibodies
  • Host
    Rat
  • Species
    Rat, Rats
  • Alternative name
    Antibody toRAT MDM2
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    MDM2 proto-oncogene
  • Synonyms gene name
    • mouse double minute 2, human homolog of; p53-binding protein
    • Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse)
    • Mdm2 p53 binding protein homolog (mouse)
    • MDM2 proto-oncogene, E3 ubiquitin protein ligase
  • Synonyms
  • Locus
  • Discovery year
    1993-12-10
  • Entrez gene record
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Zinc fingers RANBP2-type
    • Ring finger proteins
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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