Anti-PSD95 (Tyr236 + Tyr240), ALEXA Fluor 594

• Catalog number
  GENTObs-3349R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  PSD95 Tyr236 + Tyr240
• Specificity
  This antibody reacts specifically with PSD95 (Tyr236 + Tyr240)
• Modification
  Phosphorylation
• Modification site
  Tyr236 + Tyr240
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  N/A
• Antigen Source
  KLH conjugated synthetic phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240
• Gene ID
  1742
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  Discs large homolog 4; DLG 4; DLG4; Human post-synaptic density protein 95 ; Postsynaptic density protein 95; PSD 95; PSD-95; SAP 90; SAP90; Synapse associated protein 90.
• Also known as
  PSD95 (Tyr236 + Tyr240) Antibody
• Other name
  Anti-PSD95 (Tyr236 + Tyr240)
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  PSD95   Tyr236   Tyr240  
• Gene symbol
  DLG4
• Short name
  Anti-PSD95 (Tyr236 + Tyr240)
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  PSD95 (Tyr236 + Tyr240) Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2903
• Gene
  DLG4
• Long gene name
  discs large MAGUK scaffold protein 4
• Synonyms gene name
  • discs, large homolog 4 (Drosophila)
  • discs large homolog 4
• Synonyms
  • PSD-95
  • PSD95
  • SAP90
  • SAP-90
• GenBank acession
  • U83192
• Locus
  17p13.1
• Discovery year
  1995-11-07
• Entrez gene record
  1742
• Pubmed identfication
  • 9286702
• RefSeq identity
  • NM_001365
• Classification
  • Membrane associated guanylate kinases
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000134327

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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