anti-PRMT2 Antibody

• Catalog number
  29-206
• Price
  Please ask
• Size
  100 ug

• Gene info
  The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis and it exerts this effect by blocking nuclear export of IkappaB-alpha through a leptomycin-sensitive pathway, increasing nuclear IkappaB-alpha and decreasing NF-kappaB DNA binding. PRMT2 also rendered cells susceptible to apoptosis by cytokines or cytotoxic drugs, likely due to its effects on NF-kappaB.
• Gene names
  PRMT2, HRMT1L1
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by protein A chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PRMT2.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  PRMT2 antibody can be used for detection of PRMT2 by ELISA at 1:1562500. PRMT2 antibody can be used for detection of PRMT2 by western blot at 0.625 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PRMT2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  46255047
• Ncbi nr
  NP_001526
• KDa
  48 kDa, 49 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  3275
• GENE symbol
  PRMT2
• Antigene name
  protein arginine methyltransferase 2
• Source
  Homo sapiens
• Protein nr
  P55345
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PRMT2  
• Gene symbol
  PRMT2
• Short name
  anti-PRMT2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPRMT2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:5186
• Gene
  PRMT2
• Long gene name
  protein arginine methyltransferase 2
• Synonyms gene
  • HRMT1L1
• Synonyms gene name
  • HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1
  • HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae)
• Synonyms
  • MGC111373
• GenBank acession
  • U80213
• Locus
  21q22.3
• Discovery year
  1996-10-02
• Entrez gene record
  3275
• Pubmed identfication
  • 9545638
• RefSeq identity
  • NM_001535
• Classification
  • 7BS protein arginine methyltranferases
• VEGA ID
  OTTHUMG00000048806

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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