Presenilin 1 Antibody
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Catalog number3481-100
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PricePlease ask
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Size100 µg
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Antibody TargetPresenilin 1
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Target Alternative NamePSEN1, Presenilin-1; PS-1; Protein S182; Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12; PS1-CTF12
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide surrounding amino acid 296 of human Presenilin 1
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AccessionP49768
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Gene Id5663
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (2-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes Presenilin 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
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DescriptionPresenilin 1 and presenilin 2 are transmembrane proteins belonging to the presenilin family. Mutation of presenilin genes has been linked to early onset of Alzheimer’s disease, probably functioning throμgh its associated g-secretase activity for amyloid-β protein processing. Endogenous presenilin mainly exists in a heterodimeric complex formed from the endoproteolytically processed N-terminal (34 kDa) and C-terminal (~20 kDa) fragments.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPARL, PSEN1, HM13
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Short namePresenilin 1 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namePresenilin 1 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namepresenilin associated rhomboid like
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Synonyms gene
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Synonyms gene name
- presenilin associated, rhomboid-like
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-09-03
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Entrez gene record
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RefSeq identity
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Classification
- Rhomboid family
Gene info
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Identity
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Gene
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Long gene namepresenilin 1
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Synonyms gene
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Synonyms gene name
- Alzheimer disease 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1992-11-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Peptidase family A22
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namehistocompatibility minor 13
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-09-17
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Peptidase family A22
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data