PGC-1alpha Antibody
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Catalog number3934-30T
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PricePlease ask
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Size30 µg
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Antibody TargetPGC-1alpha
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Target Alternative Nameperoxisome proliferator-activated receptor gamma coactivator 1-alpha, PPAR Gamma Coactivator-1, Pgc-1alphaa, PPAR gamma coactivator variant form, PGC-1-alpha, PPARGC-1-alpha, PPAR-gamma coactivator 1-alpha
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceSynthetic peptide surrounding amino acid 766 of mouse PGC-1alpha
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AccessionNP_032930.1
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Gene Id19017
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation30 µg (0.5 mg/ml) affinity purified rabbit anti-PGC-1alpha polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal
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PurificationAffinity purified
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ApplicationWestern blot
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Positive ControlJurkat cell lysate
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Application And UsagesWestern blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Jurkat cell lysate can be used as a positive control.
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DescriptionThe protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may also be involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPGC, PPARGC1A
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Short namePGC-1alpha Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namePGC-1alpha (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameprogastricsin
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Synonyms gene name
- progastricsin (pepsinogen C)
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Classification
- Pepsinogens
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePPARG coactivator 1 alpha
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Synonyms gene
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Synonyms gene name
- peroxisome proliferative activated receptor, gamma, coactivator 1
- peroxisome proliferative activated receptor, gamma, coactivator 1, alpha
- peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-08-02
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data