Anti-PP2A alpha+beta(Tyr307), ALEXA Fluor 594

• Catalog number
  GENTObs-6419R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  PP2A alpha + beta Tyr307
• Specificity
  This antibody reacts specifically with PP2A alpha+beta(Tyr307)
• Modification
  Phosphorylation
• Modification site
  Tyr307
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Cytoplasm, Nucleus
• Antigen Source
  KLH conjugated synthetic phosphopeptide derived from human PPP2CA around the phosphorylation site of Tyr307
• Gene ID
  5520, 5516
• Swiss Prot
  N/A
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit. [provided by RefSeq, Jul 2008].
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  PP2A alpha phospho Y307; p-PP2A alphaY307; PP2A A; PP2A alpha; PP2A B; PP2A beta; PP2Ac; PP2C alpha; PP2C beta; PP2CA; PP2CB; PPP2CA; PPP2CB; Protein phosphatase 2 formerly 2A catalytic subunit alpha isoform; Protein phosphatase 2 formerly 2A catalytic subunit beta isoform; Protein phosphatase 2; Protein phosphatase 2 catalytic subunit alpha isoform; Protein phosphatase 2 catalytic subunit beta isoform; Protein Phosphatase 2A; Protein phosphatase type 2A catalytic subunit; Replication protein C; RP C; Serine/threonine protein phosphatase 2A catalytic subunit alpha isoform; Serine/threonine protein phosphatase 2A catalytic subunit beta isoform; Serine/threonine protein phosphatase.
• Also known as
  PP2A alpha+beta(Tyr307) Antibody
• Other name
  Anti-PP2A alpha+beta(Tyr307)
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  The Anti-PP2A alpha+beta(Tyr307) is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.

• Gene target
  PP2A   alpha+beta   Tyr307  
• Gene symbol
  PPP2R1B, PPP2R1A
• Short name
  Anti-PP2A alpha+beta(Tyr307)
• Technique
  anti-, anti, antibody to, antibodies
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  PP2A alpha+beta(Tyr307) Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9303
• Gene
  PPP2R1B
• Long gene name
  protein phosphatase 2 scaffold subunit Abeta
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
  • protein phosphatase 2 regulatory subunit A, beta
• Synonyms
  • PR65B
  • PP2A-Abeta
• Synonyms name
  • PP2A-A-beta
  • protein phosphatase 2A, regulatory subunit A, beta isoform
• GenBank acession
  • AF087438
• Locus
  11q23.1
• Discovery year
  1993-01-25
• Entrez gene record
  5519
• Pubmed identfication
  • 2159327
  • 9795170
• RefSeq identity
  • NM_002716
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000166741

Gene info

• Identity
  HGNC:9302
• Gene
  PPP2R1A
• Long gene name
  protein phosphatase 2 scaffold subunit Aalpha
• Synonyms gene name
  • protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
• Synonyms
  • PR65A
  • PP2A-Aalpha
  • PP2AA
• Synonyms name
  • protein phosphatase 2A, regulatory subunit A, alpha isoform
  • protein phosphatase 2, 65kDa regulatory subunit A
  • protein phosphatase 2A structural subunit A, alpha isoform
• Locus
  19q13.41
• Discovery year
  1993-01-25
• Entrez gene record
  5518
• RefSeq identity
  • NM_014225
• Classification
  • STRIPAK complex
  • Protein phosphatase 2 scaffold subunits
  • Armadillo like helical domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000137367

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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