anti-PLEKHM3 Antibody

• Catalog number
  5487
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PLEKHM3 Antibody: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
• Gene names
  PLEKHM3 Antibody: DAPR, PLEKHM1L, Pleckstrin homology domain-containing family M member 3, PH domain-containing family M member 3
• Antibodie s label
  unlabelled serum
• Purity
  PLEKHM3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PLEKHM3 antibody was made against a 13 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM3.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  PLEKHM3 antibody can be used for detection of PLEKHM3 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  PLEKHM3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PLEKHM3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  172046173
• Ncbi nr
  Q6ZWE6
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  389072
• GENE symbol
  PLEKHM3
• Antigene name
  pleckstrin homology domain containing, family M, member 3
• Source
  Homo sapiens
• Protein nr
  Q6ZWE6
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PLEKHM3  
• Gene symbol
  PLEKHM3
• Short name
  anti-PLEKHM3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPLEKHM3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:34006
• Gene
  PLEKHM3
• Long gene name
  pleckstrin homology domain containing M3
• Synonyms gene
  • PLEKHM1L
• Synonyms gene name
  • pleckstrin homology domain containing, family M, member 1-like
  • pleckstrin homology domain containing, family M, member 3
• Synonyms
  • DAPR
• Synonyms name
  • differentiation associated protein
• GenBank acession
  • AK057612
• Locus
  2q33.3
• Discovery year
  2008-02-28
• Entrez gene record
  389072
• Pubmed identfication
  • 19028694
• RefSeq identity
  • NM_001080475
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000154781

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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