anti-PIWI-L2 Antibody

• Catalog number
  6031
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PIWI-L2 Antibody: PIWI-L2 is a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that are crucial for the biogenesis and function of small non-coding RNAs and play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. PIWI-L2 has been implicated in multiple roles including stem cell self-renewal and is highly expressed in many breast cancers. In these tumors, PIWI-L2 silences the expression of STAT3, a regulator of Bcl-XL and cyclin D1, allowing the proliferation and survival of breast cancer stem cells. Recent studies have shown that overexpression of PIWI-like proteins are potential biomarkers for colon and other cancers.
• Gene names
  PIWI-L2 Antibody: CT80, HILI, mili, PIWIL1L, Piwi-like protein 2, CT80
• Antibodie s label
  unlabelled serum
• Purity
  PIWI-L2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PIWI-L2 antibody was made against a 14 amino acid synthetic peptide near the center of human PIWI-L2.
• Immuno application
  ELISA, immuno-histo-chemistry
• Antibody advice
  PIWI-L2 antibody can be used for detection of PIWI-L2 by immunohistochemistry at 5 ug/mL.
• Suspention pH azide
  PIWI-L2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PIWI-L2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  24431985
• Ncbi nr
  NP_00129193
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  55124
• GENE symbol
  PIWIL2
• Antigene name
  piwi-like 2
• Source
  Homo sapiens
• Protein nr
  Q8TC59
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PIWI-L2  
• Gene symbol
  PIWIL2-DT, PIWIL1, MRPL37, PIWIL2, KLK5, PPFIBP1, MICALL2, ZACN, GLDN, CXCR3
• Short name
  anti-PIWI-L2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPIWI-L2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55522
• Gene
  PIWIL2-DT
• Long gene name
  PIWIL2 divergent transcript
• Locus
  8p21.3
• Discovery year
  2021-03-18
• Entrez gene record
  100507071
• RefSeq identity
  • NR_134293
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:9007
• Gene
  PIWIL1
• Long gene name
  piwi like RNA-mediated gene silencing 1
• Synonyms gene name
  • piwi (Drosophila)-like 1
  • piwi-like 1 (Drosophila)
• Synonyms
  • PIWI
  • HIWI
  • CT80.1
• GenBank acession
  • AF104260
• Locus
  12q24.33
• Discovery year
  2000-02-11
• Entrez gene record
  9271
• Pubmed identfication
  • 9851978
  • 12906857
• Classification
  • Piwi like RNA-mediated gene silencing family
• VEGA ID
  OTTHUMG00000168382

Gene info

• Identity
  HGNC:14034
• Gene
  MRPL37
• Long gene name
  mitochondrial ribosomal protein L37
• Synonyms
  • RPML2
  • MRP-L2
• GenBank acession
  • AB051344
• Locus
  1p32.3
• Discovery year
  2001-02-28
• Entrez gene record
  51253
• Pubmed identfication
  • 10600119
• RefSeq identity
  • NM_016491
• Classification
  • Large subunit mitochondrial ribosomal proteins
  • Mitochondrial ribosomal proteins
• VEGA ID
  OTTHUMG00000008118

Gene info

• Identity
  HGNC:17644
• Gene
  PIWIL2
• Long gene name
  piwi like RNA-mediated gene silencing 2
• Synonyms gene name
  • piwi-like 2 (Drosophila)
• Synonyms
  • HILI
  • FLJ10351
  • Mili
  • CT80
• Synonyms name
  • Hiwi-like
  • cancer/testis antigen 80
• GenBank acession
  • AK001213
• Locus
  8p21.3
• Discovery year
  2002-04-26
• Entrez gene record
  55124
• Pubmed identfication
  • 11279525
  • 12906857
• Classification
  • Piwi like RNA-mediated gene silencing family
• VEGA ID
  OTTHUMG00000097767

Gene info

• Identity
  HGNC:6366
• Gene
  KLK5
• Long gene name
  kallikrein related peptidase 5
• Synonyms gene name
  • kallikrein 5
• Synonyms
  • SCTE
  • KLK-L2
• GenBank acession
  • AF135028
• Locus
  19q13.41
• Discovery year
  2000-03-16
• Entrez gene record
  25818
• Pubmed identfication
  • 10514489
  • 10608802
  • 16800724
  • 17012259
• RefSeq identity
  • NM_012427
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000183097

Gene info

• Identity
  HGNC:9249
• Gene
  PPFIBP1
• Long gene name
  PPFIA binding protein 1
• Synonyms gene name
  • PTPRF interacting protein, binding protein 1 (liprin beta 1)
• Synonyms
  • L2
  • hSGT2
  • hSgt2p
  • SGT2
• Synonyms name
  • liprin beta 1
• GenBank acession
  • AF034802
• Locus
  12p11.23-p11.22
• Discovery year
  1998-10-23
• Entrez gene record
  8496
• Pubmed identfication
  • 9624153
  • 11836260
• RefSeq identity
  • NM_003622
• Classification
  • Sterile alpha motif domain containing
• VEGA ID
  OTTHUMG00000169207

Gene info

• Identity
  HGNC:29672
• Gene
  MICALL2
• Long gene name
  MICAL like 2
• Synonyms
  • MGC46023
  • FLJ23471
  • MICAL-L2
  • JRAB
• Synonyms name
  • junctional Rab13-binding protein
• GenBank acession
  • BC037988
• Locus
  7p22.3
• Discovery year
  2006-11-24
• Entrez gene record
  79778
• Pubmed identfication
  • 12110185
  • 16525024
• RefSeq identity
  • NM_182924
• Classification
  • LIM domain containing
• VEGA ID
  OTTHUMG00000119021

Gene info

• Identity
  HGNC:29504
• Gene
  ZACN
• Long gene name
  zinc activated ion channel
• Synonyms gene
  • LGICZ1
• Synonyms gene name
  • ligand-gated ion channel, zinc activated 1
  • zinc activated ligand-gated ion channel
• Synonyms
  • LGICZ
  • L2
  • ZAC
  • ZAC1
• GenBank acession
  • AK122638
• Locus
  17q25.1
• Discovery year
  2006-01-31
• Entrez gene record
  353174
• Pubmed identfication
  • 12381728
  • 16083862
• RefSeq identity
  • NM_180990
• Classification
  • Zinc activated channels
• VEGA ID
  OTTHUMG00000157186

Gene info

• Identity
  HGNC:29514
• Gene
  GLDN
• Long gene name
  gliomedin
• Synonyms gene
  • COLM
• Synonyms gene name
  • collomin
• Synonyms
  • CRG-L2
  • CLOM
  • colmedin
  • UNC-122
• GenBank acession
  • AY358144
• Locus
  15q21.2
• Discovery year
  2004-05-18
• Entrez gene record
  342035
• Pubmed identfication
  • 16039564
  • 12642876
• RefSeq identity
  • NM_181789
• VEGA ID
  OTTHUMG00000131746

Gene info

• Identity
  HGNC:4540
• Gene
  CXCR3
• Long gene name
  C-X-C motif chemokine receptor 3
• Synonyms gene
  • GPR9
• Synonyms gene name
  • G protein-coupled receptor 9
  • chemokine (C-X-C motif) receptor 3
• Synonyms
  • CKR-L2
  • CMKAR3
  • IP10-R
  • MigR
  • CD183
• GenBank acession
  • U32674
• Locus
  Xq13.1
• Discovery year
  1994-11-01
• Entrez gene record
  2833
• Pubmed identfication
  • 8666380
  • 9064356
• Classification
  • C-X-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000033326

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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