anti-SkiP Antibody

• Catalog number
  2261
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  SkiP Antibody: TGF-beta and the bone morphogenic proteins (BMPs) are key signaling proteins that regulate numerous cellular processes such as embryonic development and tumorigenesis. Both signal through the Smad protein family and are negatively regulated by Ski and SnoN, two related proto-oncoproteins. Ski functions by binding to the Smad proteins activated by TGF-beta and the (BMPs) and preventing their phosphorylation, inhibiting their ability to bind DNA and activate the transcription of downstream genes. SkiP was originally identified as a Ski-interacting protein and was later found to augment the signals induced by TGF-beta but inhibit transcription induced by BMP-2 in C2C12 cells, suggesting that SkiP is a key player in the signaling cascades inititated by TGF-beta and the BMP protein family.
• Gene names
  SkiP Antibody: Bx42, SKIP, Prp45, SKIIP, PRPF45, NCOA-62, SNW domain-containing protein 1, Nuclear protein SkiP
• Antibodie s label
  unlabelled serum
• Purity
  SkiP Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  SkiP antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human SkiP.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  SkiP antibody can be used for detection of SkiP by Western blot at 0.5 - 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 20 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  SkiP Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  SkiP antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  6912676
• Ncbi nr
  NP_036377
• Vial with antibody
  in solution
• NCBI GENE nr
  22938
• GENE symbol
  SNW1
• Antigene name
  SNW domain containing 1
• Source
  Homo sapiens
• Protein nr
  Q13573
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SkiP  
• Gene symbol
  SPHKAP, INPP5K, SNW1
• Short name
  anti-SkiP Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toSkiP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:30619
• Gene
  SPHKAP
• Long gene name
  SPHK1 interactor, AKAP domain containing
• Synonyms
  • SKIP
• Synonyms name
  • sphingosine kinase type 1-interacting protein
• Locus
  2q36.3
• Discovery year
  2007-12-06
• Entrez gene record
  80309
• Pubmed identfication
  • 12080051
  • 11214970
• RefSeq identity
  • NM_030623
• Classification
  • A-kinase anchoring proteins
• VEGA ID
  OTTHUMG00000153584

Gene info

• Identity
  HGNC:33882
• Gene
  INPP5K
• Long gene name
  inositol polyphosphate-5-phosphatase K
• Synonyms
  • SKIP
• Synonyms name
  • skeletal muscle and kidney enriched inositol phosphatase
• Locus
  17p13.3
• Discovery year
  2008-09-09
• Entrez gene record
  51763
• Pubmed identfication
  • 10753883
  • 12536145
• RefSeq identity
  • NM_016532
• Classification
  • Phosphoinositide phosphatases
• VEGA ID
  OTTHUMG00000150648

Gene info

• Identity
  HGNC:16696
• Gene
  SNW1
• Long gene name
  SNW domain containing 1
• Synonyms gene
  • SKIIP
• Synonyms gene name
  • SKI interacting protein
• Synonyms
  • NCoA-62
  • SKIP
  • Prp45
  • PRPF45
  • Bx42
  • SKIP1
  • FUN20
• GenBank acession
  • AF045184
• Locus
  14q24.3
• Discovery year
  2004-05-25
• Entrez gene record
  22938
• Pubmed identfication
  • 8973337
  • 9632709
• RefSeq identity
  • NM_012245
• Classification
  • NTC associated proteins
  • Spliceosomal B complex
  • Spliceosomal Bact complex
  • Spliceosomal P complex
  • Spliceosomal C complex
• VEGA ID
  OTTHUMG00000171527

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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