anti-PDE9A Antibody

• Catalog number
  48-318
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.
• Gene names
  PDE9A, Pde9A1, Pde9a2, Pde9a3, Pde9a4, Phosphodiesterase 9A, Phosphodiesterase PDE9A21, HSPDE9A2
• Antibodie s label
  unlabelled serum
• Purity
  Immunoaffinity Chromatography
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Antigen
  PDE9A antibody was made against a peptide located near the internal domain of PDE9A (Human).
• Immuno application
  immuno-histo-chemistry
• Antibody advice
  PDE9A antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 5 ug/mL, and immunofluorescence starting at 10 ug/mL.
• Suspention pH azide
  PBS, 0.1% sodium azide.
• Keep at
  PDE9A antibody should be stored long term (months) at -80 grades C and short term (days) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Gibbon, Dog, Human, Monkey
• Omim nr
  6166014
• Ncbi nr
  O76083
• Vial with antibody
  in solution
• NCBI GENE nr
  5152
• GENE symbol
  PDE9A
• Antigene name
  phosphodiesterase 9A
• Source
  Homo sapiens
• Protein nr
  O76083
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PDE9A  
• Gene symbol
  PDE9A, PDE9A-AS1
• Short name
  anti-PDE9A Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPDE9A (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8795
• Gene
  PDE9A
• Long gene name
  phosphodiesterase 9A
• GenBank acession
  • AF048837
• Locus
  21q22.3
• Discovery year
  1998-06-12
• Entrez gene record
  5152
• Pubmed identfication
  • 9624146
• Classification
  • Phosphodiesterases
• VEGA ID
  OTTHUMG00000086825

Gene info

• Identity
  HGNC:40440
• Gene
  PDE9A-AS1
• Long gene name
  PDE9A antisense RNA 1
• Locus
  21q22.3
• Discovery year
  2019-09-19
• Entrez gene record
  101928284
• Classification
  • Antisense RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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