anti-Aven Antibody

• Catalog number
  2417
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Aven Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.
• Gene names
  Aven Antibody: PDCD12, Cell death regulator Aven
• Antibodie s label
  unlabelled serum
• Purity
  Aven Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Aven antibody was made against a 18 amino acid synthetic peptide from near the amino terminus of human Aven.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Aven antibody can be used for detection of Aven by Western blot at 1 ug/mL. Despite its predicted molecular weight, Aven often migrates at 55 kDa in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  Aven Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Aven antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  9966841
• Ncbi nr
  NP_065104
• Vial with antibody
  in solution
• NCBI GENE nr
  57099
• GENE symbol
  AVEN
• Antigene name
  apoptosis, caspase activation inhibitor
• Source
  Homo sapiens
• Protein nr
  Q9NQS1
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Aven  
• Gene symbol
  AVEN
• Short name
  anti-Aven Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toAven (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  apoptosis, caspase activation inhibitor, AVEN and IDBG-5324 and ENSG00000169857 and 57099, protein binding, Plasma membranes, Aven and IDBG-196731 and ENSMUSG00000003604 and 74268, AVEN and IDBG-646114 and ENSBTAG00000044029 and 512666

Gene info

• Identity
  HGNC:13509
• Gene
  AVEN
• Long gene name
  apoptosis and caspase activation inhibitor
• Synonyms
  • PDCD12
• Synonyms name
  • cell death regulator aven
  • programmed cell death 12
• GenBank acession
  • AF283508
• Locus
  15q14
• Discovery year
  2002-09-17
• Entrez gene record
  57099
• Pubmed identfication
  • 10949025
• RefSeq identity
  • NM_020371
• VEGA ID
  OTTHUMG00000129371

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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