anti-PCDHGB1 Antibody

• Catalog number
  26-397
• Price
  Please ask
• Size
  50 ug

• Gene info
  PCDHGB1 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHGB1 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
• Gene names
  PCDHGB1, MGC119466, MGC119467, MGC119469, PCDH-GAMMA-B1
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHGB1.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  PCDHGB1 antibody can be used for detection of PCDHGB1 by ELISA at 1:62500. PCDHGB1 antibody can be used for detection of PCDHGB1 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PCDHGB1 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human
• Omim nr
  14270490
• Ncbi nr
  NP_115266
• KDa
  85 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  56104
• GENE symbol
  PCDHGB1
• Antigene name
  protocadherin gamma subfamily B, 1
• Source
  Homo sapiens
• Protein nr
  Q3SY75
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PCDHGB1  
• Gene symbol
  PCDHGB1
• Short name
  anti-PCDHGB1 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toprotocadherin g subfamily B, 1 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  protocadherin gamma subfamily B, 1, PCDHGB1 and IDBG-408879 and ENSG00000254221 and 56104, calcium ion binding, Plasma membranes, PCDHGB2 and IDBG-646107 and ENSBTAG00000037968 and 100848197

Gene info

• Identity
  HGNC:8708
• Gene
  PCDHGB1
• Long gene name
  protocadherin gamma subfamily B, 1
• Synonyms
  • PCDH-GAMMA-B1
• Synonyms name
  • protocadherin gamma subfamily B, 1, isoform 2
• GenBank acession
  • AF152517
• Locus
  5q31
• Discovery year
  2000-06-28
• Entrez gene record
  56104
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018922
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000163681

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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