PANX1 Antibody (NT)
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Catalog number5308-100
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PricePlease ask
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Size100 µg
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Antibody TargetPANX1
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Target Alternative NamePannexin 1, Pannexin-1, PX1, MRS1, UNQ2529, UNQ2529/PRO6028
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Antibody TypePolyclonal
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Species ReactivitiesHuman, Mouse, Rat
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Immunogen SequenceRabbit polyclonal PANX1 antibody was raised against a 17 amino acid peptide near the amino terminus of human PANX1.
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AccessionQ96RD7
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Gene Id24145
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AppearanceColorless liquid
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FormLiquid
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Concentration1 mg/ml
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Formulation100 µg (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.
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PurificationAffinity chromatography purified via peptide column
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ApplicationWestern blot, ELISA
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Positive ControlWestern Blot: Human Ovary tissue lysate
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Application And UsagesWestern Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.
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DescriptionThe pannexin gene family encodes a second class of putative gap junction proteins and is highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedVerified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPANX1
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Short namePANX1 Antibody (NT)
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG1
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Alternative namepannexin 1 (antibody to-) (NT)
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Alternative techniqueantibodies
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Alternative to gene targetpannexin 1, MRS1 and PX1 and UNQ2529, PANX1 and IDBG-68155 and ENSG00000110218 and 24145, scaffold protein binding, Cell surfaces, Panx1 and IDBG-134948 and ENSMUSG00000031934 and 55991, PANX1 and IDBG-641615 and ENSBTAG00000012010 and 528169
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Gene info
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Identity
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Gene
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Long gene namepannexin 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-07-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pannexins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data