PAK2 Antibody
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Catalog number3443-30T
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PricePlease ask
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Size30 µg
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Antibody TargetPAK2
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Target Alternative NamePAK-2 , PAK65 , Gamma-PAK , hPAK65 , PAKgamma
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat, rabbit
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Immunogen SequenceSynthetic peptide corresponding to residues surrounding amino acid 5 of human Pak2
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AccessionAAD40374
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Gene Id5062
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot
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Application And UsagesWestern blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate (Cat.# 2601-100) can be used as a positive control. The antibody recognizes 60 kDa Pak2 of human, mouse, rat, and rabbit origins. The antibody does not cross-react with Pak1, Pak3, and Pak4-6. Reactivity to other species has not been tested.
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DescriptionThe PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. Phosphorylation of Ser21 of PAK1 or Ser20 of PAK2 regulates its binding with the adaptor protein Nck.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPAK2
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Short namePAK2 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative namep21 protein (Cdc42/Rac)-activated kinase 2 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetp21 protein (Cdc42/Rac)-activated kinase 2, PAK65 and PAKgamma, PAK2 and IDBG-71333 and ENSG00000180370 and 5062, transferase activity, nuclei, Pak2 and IDBG-153570 and ENSMUSG00000022781 and 224105, PAK2 and IDBG-634020 and ENSBTAG00000047856 and 513673
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Gene info
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Identity
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Gene
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Long gene namep21 (RAC1) activated kinase 2
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Synonyms gene name
- p21 (CDKN1A)-activated kinase 2
- p21 protein (Cdc42/Rac)-activated kinase 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-03-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data